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Immunohistochemistry - The Ageless Biotechnology is a book that is ideal for undergraduate and graduate biomedical researchers, and medical and dental health professionals. It is a detailed text, which emphasizes the laboratory and clinical implications of immunohistochemistry. The text covers the advances of immunohistochemistry from its humble origins in the 1930s up to the new decade of 2020. The book also offers a review of the immunohistochemistry detection systems with emphasis on their principles, history, and their advantages. It also stipulates the limitations and delineates the factors that need to be considered for choosing an appropriate detection system for IHC applications. The book describes current laboratory techniques and new applications for the technology. As the reader will observe, the book provides new and useful information concerning the rapidly advancing field of immunohistochemistry.

Nowadays, the Internet plays a vital role in our lives. It is currently one of the most effective media that is shifting to reach into all areas in today's society. While we move into the next decade, the future of many emerging technologies (IoT, cloud solutions, automation and AI, big data, 5G and mobile technologies, smart cities, etc.) is highly dependent on Internet connectivity and broadband communications. The demand for mobile and faster Internet connectivity is on the rise as the voice, video, and data continue to converge to speed up business operations and to improve every aspect of human life. As a result, the broadband communication networks that connect everything on the Internet are now considered a complete ecosystem routing all Internet traffic and delivering Internet data faster and more flexibly than ever before. This book gives an insight into the latest research and practical aspects of the broadband communication networks in support of many emerging paradigms/applications of global Internet from the traditional architecture to the incorporation of smart applications. This book includes a preface and introduction by the editors, followed by 20 chapters written by leading international researchers, arranged in three parts. This book is recommended for researchers and professionals in the field and may be used as a reference book on broadband communication networks as well as on practical uses of wired/wireless broadband communications. It is also a concise guide for students and readers interested in studying Internet connectivity, mobile/optical broadband networks and concepts/applications of telecommunications engineering.

Prompted by renowned poet E.D. Blodgett's deep love for and intimate experience of Prague, Praha is a poetic homage to the legendary city's vital spirit. As they build on one another, the poems in the collection lift the reader over the threshold of purely mythic understanding and into the heart of one of Europe's loveliest and most venerable cities. Each poem is accompanied by a translation into Czech, encouraging even those who do not know the language to immerse themselves in its sound. Superbly complemented by the mysteriously eloquent paintings of Czech artist Robert Kessner, Praha offers the moods of Prague in its many seasons and in all its magic.

Resonant Space constellates the martial, ritual, and theatrical elements of the Chinese martial arts with the practice of contemporary theatre and dance. This interdisciplinary approach blends the embodied experiences of the author, a lifelong student of the Chinese martial arts and a theatre director and dance dramaturg, with the study of Chinese cultural history. This is a work for scholars and practitioners of the Chinese martial arts, of contemporary dance and theatre, and for scholars of Chinese religion and cultural history.

In the business environment of any entity, there is an environment of natural competitiveness, leading people to want to stand out, even if they deserve to use negative behaviors towards other collaborators as a result of stigmatism created and carried since the beginning of human settlements. The objective of the research is to carry out an analysis of discrimination at work, encompassing an ethical perspective, taking as a case study in the Province of Santo Domingo. An explanatory and comparative analysis approach based on the data obtained by the Center for Information and Technological Management of Holguín on the city is used in the methodology. These stigmas related to discrimination are pointed out, generating a presence in different sectors within the province of Santo Domingo de los Tsáchilas, where high levels of inequality are evidenced by being part of a society where human beings are pigeonholed based on a series of prejudices. Finally, it is possible to determine a clear sample of high discrimination against pregnant women, young people and people with special abilities as a result of reasons related to the personal or collective benefit of the workers of a company.

Les typo-chronologies sont utilisées fréquemment pour la datation des sépultures par les professionnels qui officient en archéologie funéraire. Elles concernent les éléments constitutifs des tombes : positions des défunts, contenants, rituels, aménagements et architectures funéraires de surface ou interne à la fosse. D’autres approches et méthodes y sont associées (radiocarbone, assemblages de mobilier, stratigraphie...).Les référentiels typo-chronologiques utilisés aujourd’hui sont parfois anciens et les avancées récentes de la recherche ont considérablement renouvelé la documentation en archéologie funéraire. Il a donc semblé nécessaire au Groupe d’Anthropologie et d’Archéologie Funéraire (Gaaf) de proposer de nouveaux référentiels en ce domaine à travers cet outil à destination des archéologues et des anthropologues. Il concerne les structures funéraires à inhumation, pour des périodes s’inscrivant dans un large horizon chronologique depuis la Préhistoire jusqu’à la période contemporaine. Cet ouvrage présente 46 articles, classés par grandes aires géographiques et issus des communications données lors de la 11e Rencontre du Gaaf, tenue à Tours du 3 au 5 juin 2019.

Hepatocellular carcinoma (HCC), the most common form of liver cancer, has become a major global health problem and is responsible for a steadily increasing number of cancer-related deaths. Although the risk factors for HCC development are well known and great advances have been made through HBV vaccinations, direct-acting antivirals for HCV treatment, and aflatoxin eradication programs, the overall incidence and mortality rates of HCC are still rising. To tackle the burden of HCC, it is essential to understand the principle molecular and cellular processes as well as fundamental clinical challenges. This book provides an overview on several important disease aspects. Chapter 1 reviews recent studies assessing the potential cellular origins of HCC. Chapter 2 describes the newly discovered regulatory roles of the tumor microenvironment on tumor growth and progression. Chapters 3 and 4 outline the most commonly used in vitro systems and animal models of chronic liver disease and HCC in detail. Chapter 5 provides an overview of metabolic reprogramming and dysregulation of lipid metabolism as a newly recognized hallmark of HCC. Chapter 6 details the currently accepted standards and challenges for the surgical management of HCC, while Chapter 7 provides an overview of the recent developments in the field of tyrosine kinase inhibitors. Chapter 8 discusses multidrug resistance to chemotherapy and potential approaches to overcome this clinical obstacle. The book, written by experts from several countries, addresses each topic in sophisticated detail. It will be a valuable resource for clinicians and investigators who are interested in HCC.

Debates about reading in postcolonial studies rarely discuss non-professional readers, except to secure the authority of professional reading practices. In Reading Postcolonial Literature, Hayley G. Toth places non-professional reading practices in dialogue with received academic wisdom to debunk common-sense assumptions about non-professional readers as ‘Western’ or ‘neocolonial’ consumers. Drawing on reading practices recorded in academic books, journal articles and on online book-reviewing platforms like Amazon and Goodreads, Toth draws attention to important continuities between professional and non-professional practices of reading postcolonial literature. At the same time, she highlights that non-professionals often have little desire to emulate the practices of professional postcolonial critics. Precisely by not adopting the established protocols and methods of postcolonial studies, non-professional readers call attention to the limits of dominant approaches to reading in the discipline. Across four chapters, Toth examines the relationship between reading and identity during the Rushdie affair, the difference between reading and address, the challenges posed by difficult texts and the legitimacy of non-understanding, and the reception of popular texts primarily read by non-professional audiences. Reading Postcolonial Literature demonstrates that reception matters in any claims we make about the value of reading postcolonial literature, and offers new ways forward for the practice, study and teaching of reading in the discipline.

This book explores the concept of civic stratification and examines its contemporary relevance for analysis and understanding of the functioning of rights in society. David Lockwood’s (1996) concept of civic stratification outlines the way in which the rights associated with citizenship can be a source of inequality by virtue of their formal granting or denial by the state, or by informal impediments to their full realisation. The purpose of this book is to explore the meaning and significance of this concept, and elaborate its potential in offering a framework for understanding the dynamic nature of rights. Lockwood’s model reverses Marshall’s (1950) view of citizenship as guaranteed inclusion in society and is linked to the way that the differential entitlement and the qualifying conditions associated with certain rights can be harnessed as a means of control. While both Marshall and Lockwood were principally concerned with the rights attaching to citizenship, this book extends the insights of these two authors to show how such controls apply in various ways to both citizens and non-citizens alike. Building on Lockwood’s conception of ‘moral resources’ the book set out a theoretical framework and empirical illustration of how the position of different groups within society is subject to shifting perceptions of social worth and is engaged both in claims to fuller access to rights and in justifications of their denial or removal. This book will appeal to scholars and higher-level students with relevant interests in sociolegal studies, sociology, social policy and politics. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-NoDerivatives (CC-BY-ND) 4.0 license. This publication was supported by the University of Essex’s open access fund.

Im Rahmen des Projekts Duncker & Humblot reprints heben wir Schätze aus dem Programm der ersten rund 150 Jahre unserer Verlagsgeschichte, von der Gründung 1798 bis zum Ende des Zweiten Weltkriegs 1945. Lange vergriffene Klassiker und Fundstücke aus den Bereichen Rechts- und Staatswissenschaften, Wirtschafts- und Sozialwissenschaften, Geschichte, Philosophie und Literaturwissenschaft werden nach langer Zeit wieder verfügbar gemacht – und zwar sowohl gedruckt als auch in elektronischer Form. Einige Titel sind bereits erschienen. Täglich kommen weitere hinzu. Bis Ende des Jahres wird das »Duncker & Humblot reprints«-Programm auf ca. 1.500 Bände anwachsen. Möchten Sie regelmäßig über Neuerscheinungen aus dem reprints-Programm informiert werden? Dann abonnieren Sie unseren E-Mail-Benachrichtigungsdienst.

This volume presents a collection of papers focusing on archaeological approaches to landscape in the context of the adoption of agriculture in Southwest Asia and Northwest Europe. Case studies are presented from these contrasting regions, one where the transition to farming is indigenous, and the other where the transformation is initiated externally. This allows us to consider to what extent hunter-gatherer and farmer landscapes may be different, or the degree to which apparent differences have been constructed by our expectations and traditions of interpretation. While the concept 'landscape' enjoys considerable popularity in archaeological interpretation, it is somewhat ill-defined and inconsistently used. Some have suggested that this fluidity allows landscape to be a 'usefully ambiguous concept' but at times there is a danger that this very ambiguity affords imprecision in our narratives. This is particularly important where differing traditions of archaeological interpretation meet, as, for example, in the transition from hunting and gathering to farming. The transition has been understood as a major division in archaeological practice and attitudes to 'landscape' across the transition reflect this dichotomy. The results of these debates are illuminating, and raise questions beyond the immediate geographical scope of the volume. The contrast between the two regions provides valuable comparisons between traditions of archaeological theory and interpretation and the bodies of evidence.

The proclamation of Belarusian independence on March 25, 1918, and the rival establishment of the Soviet Belarusian state on January 1, 1919, created two distinct and mutually exclusive national myths, which continue to define contemporary Belarusian society. This book examines the processes that resulted in this dual resolution in the context of World War I and the subsequent Russian Revolutions. Based on original archival material, Lizaveta Kasmach scrutinizes the development of competing concepts of Belarusian nationhood in the context of rivaling national aspirations and imperial policies. The analysis convincingly demonstrates the divisions within the nationalist movement, both politically between the moderates and socialists, and geographically between German-occupied territory with Vilna as a center versus Russian-controlled territory around Minsk. Besides the case study of Belarusian nation-building efforts, the book is a contribution to the study of the First World War in East Central Europe, approaching the war and its aftermath as a mobilizational moment in the region.

Measures to prevent vulnerable individuals from radicalizing and to rehabilitate those who have already embraced Islamist extremism have been implemented in several Middle Eastern, Southeast Asian, and European countries. This monograph describes and assesses the strengths and weaknesses of these programs and proposes steps that can be taken to promote and accelerate deradicalization processes.

The following book seeks to answer some of these questions, above all because, unlike the labor movement, little is known about the politicization of peasants at the beginning of the 20th century. In general, the investigations have described the process of worker politicization, mentioning the fundamental role played by the political parties, be it the Democratic Party, the Socialist Workers Party and the anarchist movement in the "awakening of the workers". On the other hand, they have described that the relationship between political parties and social movements was characterized by the limited autonomy of the latter around the former. This included the peasant movement, especially in its early years. But in recent decades, a series of studies have shown that agricultural workers were not "marginalized" or "absent" from national politics, but rather, the first peasant organizations were repressed and limited in their union activity, especially among the years 1938-1952