Open Access Books

Rudos contra científicos pretende ser historia política e historia cultural. Su objeto de estudio es doble: por un lado analiza la actuación política de la comunidad universitaria durante la Revolución entre 1910 y 1920, intentando explicar su buena relación con Porfirio Díaz, su antimaderismo, las razones de su apoyo a Huerta y el creciente entendimiento con la facción carrancista. En este sentido es un trabajo innovador, pues es el primero en estudiar la participación en un proceso revolucionario de un grupo importante de la clase media urbana, llegando a conclusiones que contradicen el supuesto revolucionarismo de los jóvenes e intelectuales de la época. Por otro lado, se revisa la historia de la Universidad Nacional entre 1910 y 1920, con espeicial atención a su evolución curricular y pedagógica. Sobre todo, se analiza la transformación de una universidad fundada por Justo Sierra y recreada por José Vasconcelos.

« Trouver une forme qui accommode le désordre, telle est aujourd'hui la tâche de l'artiste. » La formule de Samuel Beckett sert de ligne directrice à cette réflexion collective sur la prose narrative de l'écrivain, attentive à l'évolution de sa poétique. Prenant acte de la résistance des textes à la lecture, l'étude décrit leur organisation par la combinaison de deux ressorts fondamentaux : les opérations de configuration, qui conditionnent l'appréhension de faits de style liant texture et structure ; un mode de progression fortement thématisé, impliquant l'énonciation elle-même dans une tension entre obligation et « empêchement ». Cette dialectique de la forme et du mouvement participe du rythme gouvernant le déploiement du discours. L'analyse textuelle appliquée à différents paliers, selon divers paramètres linguistiques, permet de cerner les conditions paradoxales de la représentation, qui mettent en question le statut du sujet, l'imaginaire de la langue, les codes littéraires. Au-delà des effets de confusion, voire d'obscurité, le discours fait participer le lecteur aux jeux du langage, exploitant la palette de l'humour et de l'ironie. Le rôle croissant de l'imagination et de la perception dans la scénographie du processus d'écriture, l'évolution vers une syntaxe de la « bribe » confirment la pertinence de perspectives intersémiotiques (théâtre, peinture, musique) pour rendre compte d'une expérience esthétique toujours plus exigeante.

This Research Topic is devoted to the understanding of molecular mechanisms of Human Thyroid Cancers. Original research describing functional studies of genetic mutations that shed novel insights into the aetiology and pathogenesis of these cancers, as well as angiogenesis and tumor microenvironment, mouse models studies that describe mechanisms or novel potential therapeutic targets and biomarkers for these endocrine cancers are presented. Scopes: The scope of this Research Topic was to cover the entire field of thyroid cancers: the main focus of this topic is translational, with an emphasis on bench to bedside research. Experimental, pre-clinical and clinical research addressing the following aspects is included in this Research Topic: 1) Investigation of specific molecular patterns of thyroid tumorigenesis, which could allow the development of new directions in the field of pharmacotherapy research; 2) Emphasis on animal studies (preclinical models of human anaplastic thyroid cancers) for the validation of biomarkers with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of these malignancies, tumor microenvironment and extracellular matrix, and metastatic disease; 3) Assessment of biomarkers to predict the potential response or resistance to drug treatment (targeted cancer therapies) or to guide the follow-up of treated patients; 4) Investigation of new laboratory molecular tests (e.g. molecular techniques and applications of thyroid fine-needle aspiration biopsy) to translate in the clinical practice; In summary, specific areas of interest include: thyroid cancer genetics; genome-wide analysis; clinical and translational research; orthotopic mouse models of metastatic thyroid carcinoma; tumor microenvironment; epigenetic; biological insights of personalized medicine; novel applications of bioinformatics; large scale molecular characterization of tumors; diagnostic or prognostic biomarkers; endocrine pathology studies; thyroid fine-needle aspiration.

Scholars contributing to this special issue on “Family Communication at the End of Life” have provided evidence that communication is vital for terminally ill individuals, family members, and healthcare/palliative care specialists. Overall, the fifteen articles in this special issue focus on five questions: First, what are the trends regarding different approaches for beginning the conversation about death and dying earlier rather than later? Second, who is making the end of life decisions and how are they made? Third, how does age and disease impact the way that families communicate at the end of life? Fourth, how does good communication (i.e., satisfying for all participants, effective for addressing needs, fulfilling goals) impact the myriad of complex issues at the end of life? Fifth, what is the significance of exploring and valuing the perspective of the family members’ experiences and recollections of their communication at the end of life with their terminally ill family member as well as with the healthcare providers? Overall, the scholars emphasize that focusing on family communication at the end of life is crucial for improving medical, psychological, and relational outcomes for those dealing with the death and dying process.

What do we mean by "behavioral neuroscience?" This volume aims at providing an overview of behavioral neuroscience and deepening neuronal mechanisms and brain circuits that regulate the fundamental aspects of human behavior, such as cognitive and emotional functions. It is intended to give the reader the most up-to-date vision of how the interaction between biological mechanisms and neurocognitive processes leads to complex and highly organized behaviors.In recent years the strong impulse given to research on behavioral neuroscience has produced a large literature that documents the high level of complexity of the issue, for which it is necessary to provide a reasoned multidimensional analysis able to integrate the expertise of different disciplines.The book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. Therefore, it represents an extraordinary opportunity to target neuroscientific hot topics and to outline new horizons in the study of the relationship between brain and behavior.

W polskiej nauce prawa konstytucyjnego ustroje krajów Azji Południowo-Wschodniej były dotychczas pomijane. W monografii przedstawiono zarys funkcjonowania systemów konstytucyjnych wybranych demokracji w tym regionie. Podczas dokonywania wyboru państw poddanych badaniom najistotniejsze znaczenie miał wpływ systemu konstytucyjnego państw-kolonizatorów na współczesny kształt państwa. Przeanalizowano więc systemy konstytucyjne Malezji i Singapuru, które przyjęły parlamentarno-gabinetowy system rządów wzorowany na modelu westminsterskim. Z kolei Timor Wschodni, który przyjął konstytucję silnie wzorowaną na ustawie zasadniczej Portugalii, pozostaje istotnym punktem odniesienia dla Singapuru. Tajlandię natomiast wyróżnia to, że nigdy w znaczeniu formalnym nie została skolonizowana, jednak - zarówno przyjmując pierwszą konstytucję w 1932 roku, jak i drugą w 2007 roku - korzystała z modelu westminsterskiego. Zaprezentowane rozważania stanowią wstęp do dalszych badań nad systemami konstytucyjnymi państw Azji Południowo-Wschodniej, a przede wszystkim umożliwiają analizę funkcji parlamentów w omawianych demokracjach.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Long ignored or scorned, industrial heritage is now being given institutional recognition: old factories are being rehabilitated, mine shafts are being included in tourist itineraries and industrial objects are being made into museums. After destroying so much, people are now dreaming of preserving everything, because the vestiges of industry are seen as constituting professional or local identities that deserve to be valued. While the social sciences cannot ignore this desire for heritage that comes from below, they must not allow themselves to be overwhelmed by these singular memories. In a critical approach that brings together researchers and heritage professionals, and takes the reader on a journey from Lorraine's iron and steel industry to the North of France's coal mines, and from Turin to Billancourt, this book examines the process that transforms factories into heritage, the second life given to them by the new functions they take on, and the conditions for a history that gives pride of place to the material traces of industry.

With the support of multinational specialists, each with different background and separate field of expertise in oncology, this book had the occasion to emerge and to offer physicians, researchers and academics efficient, well-organized and updated scientific information related to the characteristics and treatment modalities of squamous cell carcinoma. It provided in-depth information regarding the comprehension of the molecular interaction of signalling pathways and new phenotypes that might result and lead to further cell proliferation and metastases. It also emphasized on the management and individualization of treatment strategies in different types of SCC, applying molecular profiling and approved protocols in order to identify new treatment opportunities. This book also discussed the potential therapeutic modalities that might arise upon understanding and exploring the role of key regulatory proteins that govern the process of cutaneous SCC progression. And Lastly, it underlined the molecular aberrations present in SCC of different organs and the possibility of emerging new therapeutic drugs by targeting these abnormalities. It is really an innovative record that combined novel information from various medical sources and mixed it to become unified in its scientific profit.

The aim of this reprint is to provide a collection of relevant recent research in the field of soft computing, involving works on different methodologies, techniques and algorithms in soft computing, machine learning, computational intelligence, and optimization. This reprint is addressed to scientists and engineers, offering open access to a variety of innovative ideas and developments, which may further motivate new research endeavors and developments in related areas.

Autorka traktuje coaching jako jedną z metod edukacji dorosłych i osadza swój wywód teoretyczny na andragogicznych koncepcjach uczenia się. Zaprezentowane badania sytuuje w kontekście teorii transformatywnego uczenia się Jacka Mezirowa. Czytelnik otrzymuje ponadto opis własnych badań empirycznych autorki, przeprowadzonych metodą studium przypadku. Na podstawie wywiadów z trzynastoma osobami poddanymi procesowi coachingu dowiaduje się: jak przebiegał proces uczenia się, jakie były jego konteksty, jakich zmian doświadczyli uczestnicy, a także jakie znaczenie miała osoba coacha. Autorka formułuje też praktyczne wskazówki dla coachów w zakresie warunków ułatwiających proces uczenia się w coachingu.

This Reprint is designed to serve as a platform for researchers, policymakers, and practitioners to disseminate their most recent findings, innovative ideas, and effective strategies to address the critical issue of water security. This volume encompasses sixteen chapters, organized into four principal thematic areas: Hydrochemical Characteristics and Water Quality, Impact of Human Activities on Water Resources, Water Management Strategies, and Technological Applications for Water Resource Management. By amalgamating a diverse range of studies across various geographical and contextual backgrounds, this Reprint provides a sweeping overview of the current state of water resource management and its pivotal role in sustainable development.

The discipline of aquaculture ecology is developing rapidly and has generated much valuable progress in recent decades. This reprint mainly describes the recent advances in the individual ecology of commercial aquatic organisms, the ecology of aquaculture systems, the interaction between aquaculture activities and the environment, the structure of function of microbial communities, the principles of environmental management in aquaculture ecosystems, etc. Aquaculture is one of the fastest-growing human activities, and has achieved high and predictable yields in recent decades. However, the industry is also facing numerous long-term challenges, such as environmental pollution, excessive resource consumption, etc. Aquaculture ecology aims to lay an ecological foundation for the sustainable development of aquaculture. This reprint hosts 10 papers and 1 editorial, with topics including, but not limited to, the impact of floating raft aquaculture on the hydrodynamic environment of an open sea area; the bioremediation of aquaculture wastewater using seaweed; the production environment in biofloc systems; the effects of various environmental factors, including temperature, carbonate alkalinity and protein levels in compound feed on commercial aquatic species; advances in ecology research on major integrated rice field aquaculture models in China, etc. The advances in aquaculture ecology research collected in this reprint can provide references for the sustainable development of aquaculture.

The present book provides an as yet unprecedented collection of technological advances that could form the basis for future biodiversity weather stations. The book describes a range of approaches that could make biodiversity assessment as easy as measuring temperature or rainfall in a reliable, reproducible manner. There are still quite some more steps to go – but the combination of approaches shown in the book would make it worthwhile to consider carefully when designing the next level of Global Observing Systems.