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Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage

Min Liu, Yuanyuan Li, Zhilin Deng, Ke Zhang et al. • Cell Death and Disease (2025)

Abstract Mutation in genes involved in DNA replication continuously disrupt DNA replication and give rise to genomic instability, a critical driver of oncogenesis. To prevent leukemia, immature T lymphocytes with genomic instability often u...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41419-025-07392-8

Linker-specific monoclonal antibodies present a simple and reliable detection method for scFv-based CARNK cells

Katharina Schindler, Katharina Eva Ruppel, Claudia Müller, Ulrike Koehl et al. • Molecular Therapy: Methods & Clinical Development (2024)

Chimeric antigen receptor (CAR) T cell therapies have demonstrated significant successes in treating cancer. Currently, there are six approved CAR T cell products available on the market that target different malignancies of the B cell line...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.omtm.2024.101328

Cardiovascular and metabolic outcomes associated with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Suvijak Untaaveesup, MD, Thipsukon Amnartpanich, MD, Noraworn Jirattikanwong, MD, Anchaya Boonsom, MD et al. • World Allergy Organization Journal (2025)

Background: Chronic systemic inflammation in individuals with moderate-to-severe atopic dermatitis (AD) potentially predisposes them to metabolic and cardiovascular diseases. Nevertheless, evidence with regard to such association is limited...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.waojou.2025.101035

Global variations in funding and use of hemodialysis accesses: an international report using the ISN Global Kidney Health Atlas

Anukul Ghimire, Samveg Shah, Utkarsh Chauhan, Kwaifa Salihu Ibrahim et al. • BMC Nephrology (2024)

Abstract Background There is a lack of contemporary data describing global variations in vascular access for hemodialysis (HD). We used the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) to ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12882-024-03593-z

Biological Potential of <i>Tsuga canadensis</i>: A Study on Seed, Cone Essential Oils, and Seed Lipophilic Extract

Anna Wajs-Bonikowska, Ewa Maciejczyk, Łukasz Szoka, Paweł Kwiatkowski et al. • Applied Sciences (2025)

This study investigates the essential oil (EO) isolated from the seeds and cones of Canadian hemlock (Tsuga canadensis), highlighting notable differences in their chemical composition and biological activities. The seed EO was uniquely domi...

DOAJ Open Access (DOAJ) DOI: 10.3390/app15041713

Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial

Deng-Ho Yang, Hsiang-Cheng Chen, James Cheng-Chung Wei • European Journal of Medical Research (2023)

Abstract Background Gouty arthritis (GA) is a chronic systemic disease with recurrent acute monoarthritis. In a previous study, a higher incidence of acute flares was observed during the initial marked decrease in serum urate level. Our stu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40001-022-00982-8

Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8+ T cells towards the center of human lung tumors

Demi Brownlie, Andreas von Kries, Giampiero Valenzano, Nicole Wild et al. • OncoImmunology (2023)

Lung cancer is a leading cause of cancer-related death worldwide. Despite recent advances in tissue immunology, little is known about the spatial distribution of tissue-resident lymphocyte subsets in lung tumors. Using high-parameter flow c...

DOAJ Open Access (DOAJ) DOI: 10.1080/2162402X.2023.2233402

S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis

Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie et al. • Arthritis Research & Therapy (2017)

Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes....

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-017-1426-6

Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens

Ahmed Morad Asaad, Sara A. Saied, Mohammad M. Torayah, N. I. Abu-Elsaad et al. • BMC Microbiology (2025)

Abstract Background Recent advances in nanomedicine have derived novel prospects for development of various bioactive nanoparticles and nanocomposites with significant antibacterial and antifungal properties. This study aims to investigate ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12866-025-03743-9

Worldwide productivity and research trend of publications concerning extracellular vesicles role in fibrosis: A bibliometric study from 2013 to 2022

Ya-Wen Peng, Ri Tang, Qiao-Yi Xu, Shu-Ya Mei et al. • Heliyon (2024)

Background: Fibrosis is a heavy burden on the global healthcare system. Recently, an increasing number of studies have demonstrated that Extracellular vesicles play an important role in intercellular communication under both physiological a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e24357

International Archives of Allergy and Immunology

• International Archives of Allergy and Immunology (2015)

International Archives of Allergy and Immunology provides a forum for experimental and clinical research in modern molecular and cellular allergology and immunology. Appearing monthly, the journal publishes original work in the fields of al...

OPENALEX DOI: https://doi.org/10.1159/issn.1018-2438

Basic and Clinical Immunology.

• Annals of Internal Medicine (1979)

This text and review has been updated and revised since the last edition in 1974. The normal immunologic function and disease processes are presented clearly. New features include emphasis on normal immunologic function and disease processe...

OPENALEX DOI: https://doi.org/10.7326/0003-4819-90-4-732_3

Review of Medical Microbiology and Immunology

Warren E. Levinson • Repository of the University of Ljubljana (University of Ljubljana) (2002)

Essential for USMLE review and medical microbiology coursework! Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and c...

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Current Protocols in Immunology

• Current Protocols in Immunology (2018)

Current Protocols in Immunology is a three-volume looseleaf manual that provides comprehensive coverage of immunological methods from classic to the most cutting edge, including antibody detection and preparation, assays for functional acti...

OPENALEX DOI: https://doi.org/10.1002/(issn)1934-368x

Atlas of Immunology

Julius M. Cruse, Robert E. Lewis • Springer eBooks (1999)

In the 11 years since this atlas first published, the immunology field has experienced an exponential increase in information. Besides the unprecedented advances in knowledge of cell receptors and signal transduction pathways, an avalanche ...

OPENALEX DOI: https://doi.org/10.1007/978-3-662-11196-3