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Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation

Oliver H. Bell, David A. Copland, Amy Ward, Lindsay B. Nicholson et al. • Frontiers in Immunology (2020)

Background: Whether retinal microglia can maintain or restore immune homeostasis during and after inflammation is unclear. We performed single-eye mRNA-sequencing on microglia at different timepoints following a single inflammatory stimulus...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2019.03033

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure

Cassandre Labelle-Dumais, Goutham Pyatla, Seyyedhassan Paylakhi, Nicholas G. Tolman et al. • Disease Models & Mechanisms (2020)

Glaucoma is a leading cause of blindness, affecting up to 70 million people worldwide. High intraocular pressure (IOP) is a major risk factor for glaucoma. It is well established that inefficient aqueous humor (AqH) outflow resulting from s...

DOAJ Open Access (DOAJ) DOI: 10.1242/dmm.042853

Family and community resilience: a Photovoice study

Yvonne Tan, Danielle Pinder, Imaan Bayoumi, Rifaa Carter et al. • International Journal for Equity in Health (2024)

Abstract Background Adverse childhood experiences (ACEs), in combination with adverse community environments, can result in traumatic stress reactions, increasing a person’s risk for chronic physical and mental health conditions. Family res...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-024-02142-2

High posterior tibial slope increases anterior cruciate ligament elongation in unicompartmental knee arthroplasty during early-flexion of lunge

Nan Zheng, Chunjie Xia, Huiyong Dai, Diyang Zou et al. • BMC Musculoskeletal Disorders (2025)

Abstract Background In-silico and in-vitro studies have revealed an appropriate posterior tibial slope (PTS) is critical for normal anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) tension and knee biomechanical behavi...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12891-025-08335-2

Personal Protective Equipment-Related Nasal Bridge Folliculitis in a Corona Warrior

Rajeev Sharma, Ashish Bindra, Kapil Dev Soni • Indian Journal of Neurosurgery (2022)

Nasal bridge is a common site suffering personal protective equipment-induced skin damages over face among first-line health care workers in this coronavirus disease 2019 pandemic. We hereby report folliculitis as a complication following r...

DOAJ Open Access (DOAJ) DOI: 10.1055/s-0041-1722834

Bio-Engineered Graphene-Based Cage for Efficient Local Enrichment and Biodegradation of Aqueous Organic Wastes

Jixiang Fan, Dongyun Chen, Najun Li, Qingfeng Xu et al. • Scientific Reports (2017)

Abstract Microorganism immobilization has attracted great attention as a traditional method to overcome aqueous organic wastes containing N, N-dimethylformamide (DMF). In this approach, graphene oxide was modified with functional polymer fi...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-01539-0

Maternal cardiovascular adaptation to twin pregnancy: a population-based prospective cohort study

Maria C. Adank, Zoe A. Broere-Brown, Romy Gonçalves, M. Kamran Ikram et al. • BMC Pregnancy and Childbirth (2020)

Abstract Background In women with singleton pregnancies, maternal adaptation is considered a stress test for later life cardiovascular disease. The aim of this study was to assess maternal adaptation in women with twin pregnancies compared ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12884-020-02994-w

Combinations C-shaped root canals in mandibular premolars and second mandibular molars with each other and with the complex channels of other teeth of the lower jaw according to the cone-beam computed tomography

• Эндодонтия Today (2020)

From 340 CBCT included in this study, 65 patients (19.1%) found a C-shaped root canals in the mandibular first premolars, 13 patients (3.8%) - C-shaped root canals in mandibular second premolars, 34 (10%) patients - in the mandibular second...

DOAJ Open Access (DOAJ)

Recuperação Completa de Doente com Carcinoma da Próstata Estádio IV Durante a Pandemia COVID-19

Gil Falcão, Cabrita Carneiro, Luís Campos Pinheiro • Gazeta Médica (2020)

A doença causada pelo coronavírus (COVID-19), inicialmente descrita em Wuhan, China, foi recentemente declarada pela Organização Mundial da Saúde (OMS) como uma pandemia global. A idade avançada e a presença de comorbilidades, característic...

DOAJ Open Access (DOAJ) DOI: 10.29315/gm.v7i2.328

Microenvironment‐adaptive nanodecoy synergizes bacterial eradication, inflammation alleviation, and immunomodulation in promoting biofilm‐associated diabetic chronic wound healing cascade

Lei Chen, Mengna Peng, Wei He, Xiaoli Hu et al. • Aggregate (2024)

Abstract The presence of bacterial biofilms and the occurrence of excessive inflammatory response greatly imped the healing process of chronic wounds in diabetic patients. However, effective strategies to simultaneously address these issues...

DOAJ Open Access (DOAJ) DOI: 10.1002/agt2.640

Exploring innovation landscapes: a national cross-sectional study of Swedish primary care from the viewpoint of primary care managers

Sarah Samuelson, Eva-Lisa Petersson, Cecilia Björkelund, Marcus Praetorius Björk et al. • BMC Health Services Research (2026)

Abstract Background Innovation is increasingly necessary in primary care policy, and healthcare managers play a pivotal role in translating policy ambitions into practice and shaping organisational conditions that foster innovation. The aim...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-026-14870-y

Management of Ureters Involved in Inguinal Hernias

Sarah Perz, Timothy Suttle, Puneet Sindhwani • Translation (2018)

Background: The presence of a ureter in a hernia sac presents a unique surgical challenge and can increase the likelihood of ureteral injury at the time of surgery as they are often not identified pre-operatively. Here we present our instit...

DOAJ Open Access (DOAJ) DOI: 10.46570/utjms.vol5-2018-250

Small Object Detection Algorithm Based on Improved YOLOv8 for Remote Sensing

Hao Yi, Bo Liu, Bin Zhao, Enhai Liu • IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing (2024)

Due to the limitations of small targets in remote sensing images, such as background noise, poor information, and so on, the results of commonly used detection algorithms in small target detection is not satisfactory. To improve the accurac...

DOAJ Open Access (DOAJ) DOI: 10.1109/JSTARS.2023.3339235

Motion-Compensated PET Image Reconstruction via Separable Parabolic Surrogates

Nicholas E. Protonotarios, George A. Kastis, Andreas D. Fotopoulos, Andreas G. Tzakos et al. • Mathematics (2022)

The effective resolution of positron emission tomography (PET) can be significantly degraded by patient motion during data acquisition. This is especially true in the thorax due to respiratory motion. This study concentrates on the improvem...

DOAJ Open Access (DOAJ) DOI: 10.3390/math11010055