To Observe the Structural Changes in Pulmonary Systems Like Parenchymal, Airway, Vascular and Serosal Changes among Patients with CKD Over a Period of Six Months

Overview & Synopsis

Background & Methods: The aim of the study is to observe the structural changes in pulmonary systems like parenchymal, airway, vascular and serosal changes among patients with CKD over a period of six months. The purpose of the study it to evaluate proportion of different changes taking places in pulmonary systems like parenchymal, airway, vascular and serosal changes among patients with CKD. As the variables are many and we can’t have a single anticipated proportion to estimate the sample size, we consider anticipated proportion as 50% to get the maximum of the minimum sample size. Results: Mean baseline serum creatinine was 2.19±0.69 mg/dl and after 6 months was 2.44±0.71 mg/dl. When we compared the mean values between two groups, the difference was found to be significant. It means serum creatine was elevated significantly after 6 months(<0.05). Mean baseline eGFR was 38.01±14.23 mL/min and after 6 months was 34.29±12.45 mL/min. When we compared the mean values between two groups, the difference was found to be significant. It means eGFR was reduced significantly after 6 months (<0.05). Conclusion: We included total 118 patients in our study. Out of 118 subjects, majority of them were from 51-60- and 61-70-years age group i.e.34.7% each. It if followed by 12.7% patients from above 70 years age group. Mean age was 59.44±10.33 years. Prevalence pulmonary changes at the end of 6 months were noted along with the predictors. The pulmonary changes were evaluated through chest X ray PA view, oxygen saturation through pulse oximeter, pulmonary function test. Prevalence of diabetes was 85.6%.