Piezoelectric Composite Sensors for Artificial Arteries: Toward Realistic Simulation of Vascular Mechanics

Overview & Synopsis

Flexible sensors have gained significant interest in the biomedical field due to their potential for application in medical diagnostics, human health monitoring, and artificial organ systems [1, 2]. Their unique ability to adapt to complex geometries and respond to dynamic mechanical stimuli offers a critical tool for accurately monitoring and replicating physiological conditions. This feature is crucial in medical simulation and therapeutic devices, where precise detection of mechanical deformations contributes significantly in understanding organ function and optimizing medical device performances. In this context, this study aims to develop piezoelectric flexible sensors made of silicone matrix (polydimethylsiloxane, PDMS) filled with ceramic particles (Barium Titanate, BaTiO3). The obtained piezoelectric composites are engineered to instrument an experimental vascular network model, allowing advanced monitoring of mechanical deformations in artificial arteries designed with unfilled silicone matrix [3]. Combining the inherent flexibility of silicone with the piezoelectric response of ceramic fillers, these sensors are expected to enhance the detection of mechanical deformations both within artificial arteries and at the interface with embedded medical devices, such as vascular stents. To achieve an optimized piezoelectric sensitivity and still be able to maintain a mechanical behavior comparable to that of human arteries, several processing parameters were investigated. These include the ceramic filler content, the configuration of particles (random or oriented), and the curing conditions (temperature and duration) [4]. This investigation revealed that processing parameters significantly influence the composite's mechanical properties, with the incorporation of BaTiO₃ notably enhancing the piezoelectric performance yet substantially altering the material's mechanical response. These findings underscore the crucial role of both filler content and orientation in modulating the overall performance of the composite and in achieving application-specific properties. Furthermore, ongoing cyclic tensile tests are being conducted to assess the durability and reliability of the sensor under repeated deformation cycles, simulating physiological conditions. These tests will provide crucial data for optimizing the integration of sensors within the vascular simulator, ensuring their long-term performance. In regard to the incorporation of the sensor within the simulator, tests are being first carried out on flat silicone substrates to evaluate sensor performance and adhesion. The piezoelectric and mechanical responses under cyclic deformation of the sensor-substrate assembly are also being investigated. After these preliminary tests, the sensors will be adapted for integration onto a tubular model that more closely replicates the geometry of a human artery. This progression is crucial for developing a realistic vascular simulator capable of accurately mimicking physiological conditions. These findings provide valuable insights into the fundamental mechanisms that govern the mechanical and piezoelectric behavior of silicone/ceramic composites, offering a pathway to tailoring their properties to mimic closely the mechanical characteristics of arterial tissues. This approach aims to upgrade the vascular simulator, improving the testing and validation of medical devices in a controlled environment.