Evolving Landscape on Sex Specific Status on Lung Cancer Management Moderating Effects, Risk Assessment

Overview & Synopsis

The literature hasn’t given enough consideration to the connection between sex and the onset, prognosis, and course of treatment of lung cancer. Research on diseases associated with tobacco use has predominated, even though lung cancer that is not tied to smoking is on the rise and disproportionately affects women. However, depending on a patient’s sex, systemic therapy can have different effects and results, particularly when immunotherapy and chemotherapy are used. Further research is needed to fully comprehend these variances and address the rapidly changing lung cancer demographics worldwide. These results also highlight the growing awareness of the need for individualized therapies that account for variations in response and outcome related to sex.