The Search for Antifungals from Amazonian Trees: A Bio-Inspired Screening
Overview & Synopsis
The anti-fungal activity of 60 extracts from 15 tree species in the French Guiana rainforest against human and wood-rotting fungi was studied. In this way (+)-mopanol (1) was isolated from the ethyl acetate extract of Peltogyne sp. (Caesalpiniaceae) wood. This work demonstrated that (1) the natural durability of wood can indeed guide the search for antifungal agents, (2) that extracts selected in this bio-inspired process exhibit a broad spectrum of antifungal activity and (3) that the method allows for the isolation of strongly active antifungals.
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hal.science)
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Document Information
| Document Title | The Search for Antifungals from Amazonian Trees: A Bio-Inspired Screening |
|---|---|
| Author / Organization | Charlie Basset, Véronique Eparvier, Laila Espindola |
| Subject & Discipline | Multidisciplinary Academic Open Research |
| Categories | Science & Mathematics |
| Publication Year | 2015 |
| License / Rights | Open Access / Creative Commons |
| Resource Verification | Listed PDF (Verification Pending) |
| Original Host Website |
HAL Open Science
(hal.science)
|
| File Format | application/pdf (Portable Document Format) |
| Language | EN |
| Catalog ID | DOC-238243 |
| Original Source Link | Visit Source Page on hal.science » |