Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Author / Organization: Rebecca Sims, Sven van Der Lee, Adam Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian Kunkle, Anne Boland, Rachel Raybould, Joshua Bis, Eden Martin, Benjamin Grenier-Boley, Stefanie Heilmann-Heimbach, Vincent Chouraki, Amanda Kuzma, Kristel Sleegers, Maria Vronskaya, Agustin Ruiz, Robert Graham, Robert E Olaso, Per Hoffmann, Megan Grove, Badri Vardarajan, Mikko Hiltunen, Markus M. Nöthen, Charles White, Kara Hamilton-Nelson, Jacques Epelbaum, Wolfgang Maier, Seung-Hoan Choi, Gary Beecham, Cécile Dulary, Stefan Herms, Albert Smith, Cory Funk, Céline Derbois, Andreas Forstner, Shahzad Ahmad, Hongdong Li, Delphine Bacq, Denise Harold, Claudia Satizabal, Otto Valladares, Alessio Squassina, Rhodri Thomas, Jennifer Brody, Liming Qu, Pascual Sanchez-Juan, Taniesha Morgan, Frank Wolters, Yi Zhao, Florentino Sanchez Garcia, Nicola Denning, Myriam Fornage, John Malamon, Maria Candida Deniz Naranjo, Elisa Majounie, Thomas Mosley, Beth A. Dombroski, David Wallon, Michelle Lupton, Josée Dupuis, Patrice Whitehead, Laura Fratiglioni, Christopher Medway, Xueqiu Jian, Shubhabrata Mukherjee, Lina Keller, Kristelle Brown, Honghuang Lin, Laura Cantwell, Francesco Panza, Bernadette Mcguinness, Sonia Moreno-Grau, Jeremy Burgess, Vincenzo Solfrizzi, Petra Proitsi, Hieab Adams, Mariet Allen, Davide Seripa, Pau Pastor, L Adrienne Cupples, Nathan Price, Didier Hannequin, Ana Frank-García, Daniel Lévy, Paramita Chakrabarty, Paolo Caffarra, Ina Giegling, Alexa Beiser, Vilmantas Giedraitis, Harald Hampel, Melissa E. Garcia, Xue Wang, Lars Lannfelt, Patrizia Mecocci, Gudny Eiriksdottir, Paul Crane, Florence Pasquier, Virginia Boccardi, Isabel Henández, Robert Barber, Martin Scherer, Lluis Tarraga, Perrie Adams, Markus Leber, Yuning Chen, Marilyn Albert, Steffi Riedel-Heller, Valur Emilsson, Duane Beekly, Anne Braae, Reinhold Schmidt, Deborah Blacker, Carlo Masullo, Helena Schmidt, Rachelle Doody, Gianfranco Spalletta, W T Longstreth Jr, Thomas Fairchild, Paola Bossù, Oscar López, Matthew P Frosch, Eleonora Sacchinelli, Bernardino Ghetti, Qiong Yang, Ryan Huebinger, Frank Jessen, Shuo Li, M Ilyas Kamboh, Oscar Sotolongo-Grau, Mindy Katz, Chris Corcoran, Melanie Dunstan, Amy Braddel, Charlene Thomas, Alun Meggy, Rachel Marshall, Amy Gerrish, Jade Chapman, Miquel Aguilar, Sarah Taylor, Matt Hill, Mònica Díez Fairén, Angela Hodges, Bruno Vellas, Hilkka Soininen, Iwona Kloszewska, Makrina Daniilidou, James Uphill, Yogen Patel, Joseph Hughes, Jenny Lord, James Turton, Annette M. Hartmann, Roberta Cecchetti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Carlo Caltagirone, Maria Donata Orfei, Antonio Ciaramella, Sabrina Pichler, Manuel Mayhaus, Wei Gu, Alberto Lleó, Juan Fortea, Rafael Blesa, Imelda Barber, Keeley Brookes, Chiara Cupidi, Raffaele Giovanni Maletta, David Carrell, Sandro Sorbi, Susanne Moebus, Maria Joana Urbano, Alberto Pilotto, Johannes Kornhuber, Paolo Bosco, Stephen Todd, David Craig, Janet Johnston, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Nick Fox, John Hardy, Roger Albin, Liana G Apostolova, Steven Arnold, Sanjay Asthana, Craig Atwood, Clinton Baldwin, Lisa L Barnes, Sandra Barral, Thomas Beach, James Becker, Eileen Bigio, Thomas Bird, Bradley Boeve, James Bowen, Adam Boxer, James Burke, Jeffrey Burns, Joseph D. Buxbaum, Nigel Cairns, Chuanhai Cao, Chris Carlson, Cynthia Carlsson, Regina Carney, Minerva Carrasquillo, Steven Carroll, Carolina Ceballos Diaz, Helena Chui, David Clark, David Cribbs, Elizabeth Crocco, Charles Decarli, Malcolm Dick, Ranjan Duara, Denis Evans, Kelley Faber, Kenneth Fallon, David Fardo, Martin Farlow, Steven Ferris, Tatiana Foroud, Douglas Galasko, Marla Gearing, Daniel H. Geschwind, John Gilbert, Neill Graff-Radford, Robert Green, John Growdon, Ronald Hamilton, Lindy Harrell, Lawrence Honig, Matthew Huentelman, Christine Hulette, Bradley T. Hyman, Gail Jarvik, Erin Abner, Lee-Way Jin, Gyungah Jun, Anna Karydas, Jeffrey Kaye, Ronald Kim, Neil Kowall, Joel Kramer, Frank Laferla, James Lah, James Leverenz, Allan Levey, Ge Li, Andrew Lieberman, Kathryn Lunetta, Constantine Lyketsos, Daniel Marson, Frank Martiniuk, Deborah Mash, Eliezer Masliah, Wayne Mccormick, Susan Mccurry, Andrew Mcdavid, Ann C Mckee, Marsel Mesulam, Bruce Miller, Carol Miller, Joshua Miller, John Morris, Jill Murrell, Amanda Myers, Sid O'Bryant, John Olichney, Vernon Pankratz, Joseph Parisi, Henry Paulson, William Perry, Elaine Peskind, Aimee Pierce, Wayne Poon, Huntington Potter, Joseph Quinn, Ashok Raj, Murray Raskind, Barry Reisberg, Christiane Reitz, John Ringman, Erik Roberson, Ekaterina Rogaeva, Howard Rosen, Roger Rosenberg, Mark Sager, Andrew Saykin, Julie A Schneider, Lon S Schneider, William Seeley, Amanda Smith, Joshua Sonnen, Salvatore Spina, Robert Stern, Russell Swerdlow, Rudolph E. Tanzi, Tricia Thornton-Wells, John Q Trojanowski, Juan Troncoso, Vivianna van Deerlin, Linda van Eldik, Harry V. Vinters, Jean Paul Vonsattel, Sandra Weintraub, Kathleen Welsh-Bohmer, Kirk Wilhelmsen, Jennifer Williamson, Thomas Wingo, Randall Woltjer, Clinton Wright, Chang-En Yu, Lei Yu, Fabienne Garzia, Feroze Golamaully, Gislain Septier, Sebastien Engelborghs, Rik Vandenberghe, Peter de Deyn, Carmen Muñoz Fernadez, Yoland Aladro Benito, Hakan Thonberg, Charlotte Forsell, Lena Lilius, Anne Kinhult-Stählbom, Lena Kilander, Rosemarie Brundin, Letizia Concari, Seppo Helisalmi, Anne Maria Koivisto, Annakaisa Haapasalo, Vincent Dermecourt, Nathalie Fievet, Olivier Hanon, Carole Dufouil, Alexis Brice, Karen Ritchie, Bruno Dubois, Jayanadra Himali, C Dirk Keene, Joann Tschanz, Annette Fitzpatrick, Walter Kukull, Maria Norton, Thor Aspelund, Eric Larson, Ron Munger, Jerome Rotter, Richard Lipton, María Bullido, Albert Hofman, Thomas Montine, Eliecer Coto, Eric Boerwinkle, Ronald Petersen, Victoria Alvarez, Fernando Rivadeneira, Eric Reiman, Maura Gallo, Christopher O'Donnell, Joan Reisch, Amalia Cecilia Bruni, Donald Royall, Martin Dichgans, Mary Sano, Daniela Galimberti, Peter St George-Hyslop, Elio Scarpini, Debby Tsuang, Michelangelo Mancuso, Ubaldo Bonuccelli, Ashley Winslow, Antonio Daniele, Chuang-Kuo Wu, Oliver Peters, Benedetta Nacmias, Matthias Riemenschneider, Reinhard Heun, Carol Brayne, David C. Rubinsztein, Jose Bras, Rita Guerreiro, Ammar Al-Chalabi, Christopher Shaw, John Collinge, David Mann, Magda Tsolaki, Jordi Clarimón, Rebecca Sussams, Simon Lovestone, Michael O'Donovan, Michael Owen, Timothy Behrens, Simon Mead, Alison Goate, André G. Uitterlinden, Clive Holmes, Carlos Cruchaga, Martin Ingelsson, David A Bennett, John Powell, Todd Golde, Caroline Graff, Philip L de Jager, Kevin Morgan, Nilufer Ertekin-Taner, Onofre Combarros, Bruce Psaty, Peter Passmore, Steven Younkin, Claudine Berr, Vilmundur Gudnason, Dan Rujescu, Dennis Dickson, Jean-François Dartigues, Anita Destefano, Sara Ortega-Cubero, Hakon Hakonarson, Dominique Campion, Merce Boada, John Keoni Kauwe, Lindsay Farrer, Christine van Broeckhoven, M Arfan Ikram, Lesley Jones, Jonathan Haines, Christophe Tzourio, Lenore Launer, Valentina Escott-Price, Richard P. Mayeux, Jean-François Deleuze, Najaf Amin, Peter Holmans, Margaret Pericak-Vance, Philippe Amouyel, Cornelia M. van Duijn, Alfredo Ramírez, Li-San Wang, Jean-Charles Lambert, Sudha Seshadri, Julie Williams, Gerard D. Schellenberg
| File Format | PDF (Portable Document Format) |
|---|---|
| Publication Year | 2017 |
| Source Host |
HAL Open Science
(hal.science)
|
| License / Terms | Open Access / Creative Commons |
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