Evaluation of Thyroid Hormone Profile in CRF (Chronic Renal Failure) Patients in JLNMCH Bhagalpur

Overview & Synopsis

Background: Chronic Renal Failure (CRF) is characterised by kidney function decline. Thyroid dysfunction can induce cardiovascular abnormalities, metabolic alterations, and other serious issues in CRF. Methods: This Study was done at the Jawaharlal Nehru Medical College and Hospital in Bhagalpur between 2018 to 2020. The study looked at 100 people with CRF whose thyroid function tests came back positive. Patients with insufficient data or other thyroid problems were not included in the study. The most important ones were TSH, T3, and T4. SPSS helped us figure out how common thyroid failure is and find links between thyroid hormone levels, the length of CRF, and being on dialysis. Results: 38% of people with CRF had hypothyroidism and 12% had hyperthyroidism, according to a study. Even though T3 and T4 levels were low, the average TSH level rose by 6.3 µIU/mL. TSH and T3 levels were linked to the length of CRF and whether the person was on dialysis. These results show that people on CRF have thyroid problems and that the length of their CRF and dialysis affect the amounts of thyroid hormones. Conclusion: A lot of people with CRF have both hypothyroidism and hyperthyroidism. In CRF, TSH goes up and T3 and T4 go down because of an unbalance in the thyroid glands. Managing CRF and keeping an eye on thyroid function are very important to keep health problems from happening. Future studies need to look into what causes CRF thyroid failure and how to treat it.