Renal aging in WKY rats: Changes in Na,K-ATPase function and oxidative stress
Overview & Synopsis
It has been suggested that alterations in Na,K-ATPase mediate the development of several aging-related pathologies, such as hypertension and diabetes. Thus, we evaluated Na,K-ATPase function and HO production in the renal cortex and medulla of Wistar Kyoto (WKY) rats at 13, 52 and 91 weeks of age. Creatinine clearance, proteinuria, urinary excretion of Na and K and fractional excretion of Na were also determined.
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hal.science)
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Document Information
| Document Title | Renal aging in WKY rats: Changes in Na,K-ATPase function and oxidative stress |
|---|---|
| Author / Organization | E. J. Silva, V. Pinto, S. Simão, M.P. Serrão, J. Afonso, J. Amaral, M.J. Pinho, P. Gomes, P. Soares-Da-Silva |
| Subject & Discipline | Multidisciplinary Academic Open Research |
| Categories | Science & Mathematics |
| Publication Year | 2010 |
| License / Rights | Open Access / Creative Commons |
| Resource Verification | Listed PDF (Verification Pending) |
| Original Host Website |
HAL Open Science
(hal.science)
|
| File Format | application/pdf (Portable Document Format) |
| Language | EN |
| Catalog ID | DOC-142815 |
| Original Source Link | Visit Source Page on hal.science » |