Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease.
Overview & Synopsis
We conducted a historical cohort study of 981 first-degree relatives of 162 patients with Parkinson's disease (PD) and of 838 first-degree relatives of 147 controls representative of the population of Olmsted County, Minnesota. In addition, we studied 2,684 first-degree relatives of 411 patients with PD referred to the Mayo Clinic. Relatives were interviewed and screened for tremor either directly or through a proxy, and those who screened positive were examined or copies of their medical records were obtained to confirm the diagnosis of essential tremor (ET). We also obtained ET information from a medical records-linkage system (family study method). In the population-based sample, the risk of ET was significantly increased for relatives of patients with onset of PD
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Document Information
| Document Title | Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease. |
|---|---|
| Author / Organization | Walter A. Rocca, James H. Bower, J. Eric Ahlskog, Alexis Elbaz, Brandon R. Grossardt, Shannon K. Mcdonnell, Daniel J. Schaid, Demetrius M. Maraganore |
| Subject & Discipline | Multidisciplinary Academic Open Research |
| Categories | Science & Mathematics |
| Publication Year | 2007 |
| License / Rights | Open Access / Creative Commons |
| Resource Verification | Listed PDF (Verification Pending) |
| Original Host Website |
HAL Open Science
(hal.science)
|
| File Format | application/pdf (Portable Document Format) |
| Language | EN |
| Catalog ID | DOC-11991 |
| Original Source Link | Visit Source Page on hal.science » |