Open Access Books

Reports results of an evaluation of the content and utilization of four student mental health websites targeting K–12 and higher-education systems in California.

This book examines the role of pharmaceutical biotechnology in modern drug development, highlighting recent advancements in genomics, biopharmaceuticals, and personalized medicine. It explores key molecular and genomic technologies that are revolutionizing drug discovery, design, and delivery. The introductory chapters describe the essential molecular biology techniques, including next-generation sequencing and CRISPR applications, gene editing, synthetic biology, and their role in drug discovery. Furthermore, the book explores pharmacogenomics as a link between genomics and drug response, while also covering the discovery, production, and commercialization of biopharmaceuticals. It provides an in-depth discussion on the role of bioinformatics in analyzing genomic data for drug development, along with genomic strategies for target identification, validation, and the discovery of biomarkers essential to modern drug development. The book also highlights advancements in personalized medicine, emphasizing the use of genomic data to tailor treatments for individual patients. It discusses the design and therapeutic applications of monoclonal antibodies and explores breakthroughs in cell and gene therapies, addressing their potential and the challenges associated with disease treatment. Key Features: Provides a historical and technological perspective on pharmaceutical biotechnology and genomics Explores advanced molecular techniques, including CRISPR and next-generation sequencing, and their applications in drug discovery Discusses pharmacogenomics and the role of biomarkers in enabling personalized medicine Highlights emerging trends such as synthetic biology, gene editing, and biopharmaceutical development Addresses ethical issues and challenges in genomic research and drug development This book is intended for researchers and students of pharmaceutical sciences and biotechnology. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Knowledge has no limits and everyone has the opportunity to gain it and expand the view and horizon of understanding. Nothing in this world remains permanent, everything changes. Hence the field of morphology of the Earth (geomorphology) provides a basis for exploring, understanding and comprehending the forms and processes that occur in our surrounding. This book presents some of the ideas and understanding about geomorphology: Learn about the effect of deforestation and then reforestation on river channel morphology. Understand the composite mathematical modelling for continuous simulations of hydro-geomorphological processes. Know about the process-response models for estimation of cliff erosion and its quantitative predictions. Grow your knowledge about various geomorphometric tools that are available in freely available GIS software.

Control system engineering is a multidisciplinary discipline that applies automatic control theory to design systems with desired behaviors in control environments. Automatic control theory has played a vital role in the advancement of engineering and science. It has become an essential and integral part of modern industrial and manufacturing processes. Today, the requirements for control precision have increased, and real systems have become more complex. In control engineering and all other engineering disciplines, the impact of advanced mathematical and computational methods is rapidly increasing. Advanced mathematical methods are needed because real-world control systems need to comply with several conditions related to product quality and safety constraints that have to be taken into account in the problem formulation. Conversely, the increment in mathematical complexity has an impact on the computational aspects related to numerical simulation and practical implementation of the algorithms, where a balance must also be maintained between implementation costs and the performance of the control system. This book is a comprehensive set of articles reflecting recent advances in developing and applying advanced mathematics and computational applications in control system engineering.

This book offers a comprehensive analysis of image processing and its many applications in various fields. From improving the resolution of blurry images to identifying crop pests, optimizing water resource management, and extracting crucial details from photographs and videos, it covers a wide range of techniques and uses. Readers will be immersed in the fascinating world of image edge detection, combining color-based multidimensional scaling maps to highlight areas of saliency, and using deep learning to transform perception in driver assistance systems and autonomous vehicles. Additionally, they will explore how visual recognition can predict crack trajectories, bionic color theory, and the creation of realistic simulations of radar images. A highlight of the book is its focus on the revolutionary application of image processing in dentistry, from making precise measurements to developing next-generation dental biometrics systems. With a detailed and broad overview, this book provides readers with the tools and knowledge necessary to unlock the potential hidden in images, opening up new possibilities and applications in fields ranging from agriculture and medicine to technology and science.

Zeit ist eine Dimension sozialpädagogischen Handelns, sozialpädagogischer Forschung und Theoriebildung. Dennoch wird der ›temporal turn‹ der Sozial- und Kulturwissenschaften im sozialpädagogischen Diskurs bisher kaum aufgegriffen. Der Band geht sozialpädagogischen Zeitdiagnosen und einem ›doing time‹ im Sinne einer sozialen Herstellung von Zeit ebenso nach wie Relationierungen von Gegenwart, Vergangenheit und Zukunft. Diese Relationierungen werden sowohl in disziplinären Entwicklungen als auch auf individuell biografischer Ebene von Adressat*innen und Fachkräften verfolgt.

This volume publishes some of the texts presented at the 2nd edition of the International Congress for Young Researchers in Middle Ages, under the theme “Space(s)”, held at the University of Évora between the 13th and 15th November 2019. As in the previous volume, the texts are authored by young researchers in medieval history, coming from various academic and geographical origins and combining various scientific disciplines.

This book urges for an understanding of contemporary art as being core to creative responses which intervene in the lived experience of forced displacement. Contemporary Art and Forced Displacement explores art practice which moves beyond mere representation toward practical intervention across five key areas: language, heritage and design, pedagogy and education, law and access to justice and the archive. Focusing on art produced across three sites, each emblematic of protracted forms of displacement (Greece, Palestine and Australia), it makes clear the ways in which art operates as a vital yet underacknowledged instrument of cultural resilience. This book is ideal for researchers, scholars and practitioners interested in contemporary art and politics, contemporary art methods and practice, and migration.

La Inteligencia Artificial (IA), un agente transformador que ha irrumpido en nuestra vida cotidiana y se ha convertido en un cambio fundamental en nuestra forma de vivir, trabajar e interactuar, es también conocida como el núcleo de la cuarta revolución industrial, ya que funciona como una entidad que integra otras tecnologías. A pesar de su experiencia en educación, la IA sigue siendo un campo fértil, especialmente en el área de la enseñanza y el aprendizaje de idiomas. Este libro explora cómo la IA ha permeado la vida académica de los docentes de idiomas en diversos contextos universitarios de la República Mexicana. Las diferentes posiciones geográficas representadas por cada uno de los investigadores participantes revelan una característica distintiva de este proyecto: la diversificación de las fuentes de información, lo que permite comprender el tema y profundizar en él desde la perspectiva y la experiencia de personas diversas en diferentes contextos educativos.

Hay muchas escuelas de sabiduría en los pueblos originarios y de prestigio milenario cuyo estudio podemos dedicarnos, pero por sobre eso, la sabiduría maya-tsotsil para nosotros es lo propio, lo nuestro. ¿Qué ha impedido que conozcamos hasta hoy estas antiguas tradicio- nes nuestras? La respuesta no es muy difícil de hallar, sabido es el prejuicio que el hombre “civilizado" tiene respecto al pueblo originario, prejuicio que en México se ha dado con particular violencia y ceguera, y si a pesar de ello hemos investigado diversos aspectos de nuestras culturas originarias, lo que no podríamos aceptar sin dificultad es que los totil-me’iletik poseen eso que se llama la sabiduría.

The volume collects a full transcription, complete with notes of comments, of letters and invitations from Neapolitan scientists to the famous archaeologist Giuseppe Fiorelli (1823-1896). These documents bear witness of an intricate network of relationships among high personalities of the intelligentsia of XIX century Naples and contribute to highlight the work of Fiorelli beyond archaeology and Pompeii excavations.

The geographic environment, shaped by climate, landforms, hydrological processes, and anthropogenic influences, demands integrated approaches to capture its spatiotemporal heterogeneity and interconnected dynamics. Recent innovations—spanning remote sensing, geospatial big data, sensor networks, and multidisciplinary modeling—now enable multidimensional, multiscale observations across extended temporal and spatial ranges. These technologies facilitate the integration of data from global to microscale levels, enhancing our understanding of geographic processes and their implications for sustainable development. The following Topic compiles 44 peer-reviewed articles that exemplify cutting-edge methodologies and applications in this field. Studies employ diverse techniques, from satellite- and drone-based remote sensing to hybrid data fusion and machine learning, demonstrating the interdisciplinary nature of geographic environmental research. Key findings highlight the value of multiscale data integration in unraveling complex patterns. By integrating Earth system science with societal needs, this research trajectory aims to strengthen resilience to environmental risks and advance the United Nations Sustainable Development Goals (SDGs). This Topic underscores the transformative potential of multi-scale monitoring in deciphering geographic complexity, offering a foundation for interdisciplinary innovation and holistic environmental stewardship in an era of rapid global change.

The study analyses the quality development of teaching staff at schools. It looks at all three phases of training: Study, probation and further training. The expert's report therefore gives a comprehensive overview of the structure of further training for teachers in the Federal Republic of Germany's federal education system.

A doscientos años del nacimiento de Karl Marx, su obra y su nombre permanecen como una marca indeleble que acompaña las luchas de todos los pueblos oprimidos y explotados del mundo. Como creación heroica, dejamos en manos de los luchadores y las luchadoras por un mundo más justo una herramienta que reivindica un Marx nuestro, propio, de quienes estamos construyendo el porvenir de una nueva civilización.

Bioremediation technologies for environments contaminated by organic and inorganic pollutants are a major focus of researchers and scientists worldwide. The chemical control of agricultural pests and advocacy for sustainable agriculture have led to the development of new paradigms in environmental remediation. This book covers recent advances in the bioremediation technology of organic and inorganic pollutants in the environment.