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Showing 20 of 62 academic articles

Progressive suppression of regulated cell death defines terminal macrophage states in liver cirrhosis

Kepu Zheng, Leiyang Dai, Yanghui Wen, Haitao Jiang et al. • Annals of Medicine (2026)

Background Macrophages are central regulators of liver immunity and fibrosis; Recent single-cell studies have characterized macrophage heterogeneity in cirrhosis; however, how regulated cell death programs shape their functional transitions...

DOAJ Open Access (DOAJ) DOI: 10.1080/07853890.2026.2690717

The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

Katja Niesel, Michael Schulz, Julian Anthes, Tijna Alekseeva et al. • EMBO Molecular Medicine (2021)

Abstract The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes. Desp...

DOAJ Open Access (DOAJ) DOI: 10.15252/emmm.202013412

Elevated Eosinophils as a Feature of Inflammation Associated With Hypertension in Virally Suppressed People Living With HIV

Sepiso K. Masenga, Fernando Elijovich, Benson M. Hamooya, Selestine Nzala et al. • Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2020)

Background People living with HIV (PLWH) are at increased risk of cardiovascular disease, including hypertension, which persists despite effective plasma viral suppression on antiretroviral therapy. HIV infection is characterized by long‐te...

DOAJ Open Access (DOAJ) DOI: 10.1161/JAHA.118.011450

Scavenger receptor MARCO contributes to cellular internalization of exosomes by dynamin-dependent endocytosis and macropinocytosis

Sanae Kanno, Seishiro Hirano, Tsubasa Sakamoto, Akiko Furuyama et al. • Scientific Reports (2020)

Abstract Macrophage receptor with collagenous structure (MARCO) is a scavenger receptor class-A protein that is expressed on the cell surface of macrophages. MARCO mediates binding and ingestion of unopsonized environmental particles, inclu...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-020-78464-2