Academic Articles & Research Papers

Nanotechnology in Plant Science: To Make a Long Story Short

This mini-review aims at gaining knowledge on basic aspects of plant nanotechnology. While in recent years the enormous progress of nanotechnology in biomedical sciences has revolutionized therapeutic and diagnostic approaches, the comprehe...

Polyphenols: From Theory to Practice

Background: The importance of polyphenols in human health is well known; these compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and wine. On the other hand, the different factors that modulate the bi...

Scrolling and Self: How Self-Esteem and Physical Activity Shape the Effects of Intagram Use on Eating Behavior in Universitary Students

Introduction The use of Social Networking Sites (SNS) has been continuously increasing in recent years [1], contributing to the rise of significant behavioral and psychological issues, especially when SNS are used as a coping mechanism f...

Research software: A key (neglected) component of the digital research infrastructure ecosystem

Evaluation of Lipid Profile and Inflammatory Marker in Patients with Gastric Helicobacter pylori Infection, Ethiopia

Gelagey Baye Temesgen,1 Menakath Menon,2 Solomon Tebeje Gizaw,2 Bayu Wondimneh Yimenu,1 Melaku Mekonen Agidew3 1Department of Biomedical Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Medical Biochemistry School o...

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...

Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana

Abstract Background Poor adherence to antiretroviral therapy (ART) continues to undermine HIV treatment outcomes in sub-Saharan Africa, including Ghana. Objective This study aimed to quantify ART treatment adherence among people living with...

Thoracic electrical impedance tomography identifies heterogeneity in lungs associated with respiratory disease in cattle. A pilot study

Respiratory disease in cattle is a significant global concern, yet current diagnostic methods are limited, and there is a lack of crush-side tests for detecting active disease. To address this gap, we propose utilizing electrical impedance ...

Challenges and experience of the Ethiopian rural health extension program: implications for reform and revitalization

Abstract Background Despite remarkable gains over the past decade, mounting evidence suggests that Ethiopia’s rural health extension program (HEP) is facing serious implementation challenges. We investigated the current and potential future...

Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge

In response to acute exercise, an array of metabolites, nucleic acids, and proteins are enriched in circulation. Collectively termed “exercise factors,” these molecules represent a topical area of research given their speculated contributio...

Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media

Saccharomyces cerevisiae is an important model organism and a typical fungal representative for studies of eukaryotes. The cell cycle of yeast can be analyzed by flow cytometry, and refining the cytometric resolution of the cell cycle with ...

Unveiling Insights into the Whole Genome Sequencing of <i>Mycobacterium</i> spp. Isolated from Siamese Fighting Fish (<i>Betta splendens</i>)

This study aims to genomically elucidate six isolates of rapidly growing non-tuberculous mycobacteria (RGM) derived from Siamese fighting fish (Betta splendens). These isolates had previously undergone phenotypic and biochemical characteriz...

Longevity of dental restorations in Sjogren’s disease patients using electronic dental and health record data

Abstract Background Decreased salivary secretion is not only a risk factor for carious lesions in Sjögren’s disease (SD) but also an indicator of deterioration of teeth with every restorative replacement. This study determined the longevity...

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

ETNK1 mutations are recurrent in leukemia but how they contribute to oncogenesis is still unclear. Here, the authors show that ETNK1 mutations increase mitochondrial activity, ROS and H2AX levels and that these effects can be rescued upon p...

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia

Abstract Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting popula...

Further validation of the Chinese short Warwick Edinburgh mental wellbeing scale in the adult population of Macau: an application of classic test theory and item response theory

BackgroundThis study aims to validate the Chinese version of the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) by employing both Classical Test Theory (CTT) and Item Response Theory (IRT) approaches.MethodsData were gathered thr...

Melanopsin and Cone Photoreceptor Inputs to the Afferent Pupil Light Response

Background: Retinal photoreceptors provide the main stage in the mammalian eye for regulating the retinal illumination through changes in pupil diameter, with a small population of melanopsin-expressing intrinsically photosensitive retinal ...

Compounds of Marine Origin with Possible Applications as Healing Agents

It is well established that marine organisms consist of a great variety of active compounds that appear exclusively in the marine environment while having the ability to be vastly reproduced, irrespective of the existing conditions. As a re...

MUT-7 Provides Molecular Insight into the Werner Syndrome Exonuclease

Werner syndrome (WS) is a rare recessive genetic disease characterized by premature aging. Individuals with this disorder develop normally during childhood, but their physiological conditions exacerbate the aging process in late adolescence...