Academic Articles & Research Papers

Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality.

Large language models (LLMs) have been investigated for clinical documentation, with concerns about hallucinations and factual errors. Clinician review and revision of LLM-generated drafts are considered essential; however, the impact of su...

Argumentation approaches for explanaible AI in medical informatics

Artificial Intelligence algorithms are powerful in performing accurate predictions, but they are often considered black boxes as they do not provide any explanation about how outputs are derived from inputs or why a decision is taken. There...

Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial

BackgroundCognitive behavioral therapy (CBT) is the most effective treatment for binge eating disorder (BED) but is limited by modest efficacy and low reach of in-person delivery. Combining mindfulness training with CBT could enhance effica...

Percutaneous CT-Guided Bone Lesion Biopsy for Confirmation of Bone Metastases in Patients with Breast Cancer

We aimed to determine diagnostic accuracy of CT-guided bone lesion biopsy for the confirmation of bone metastases in patients with breast cancer and assessment of hormone receptor status in metastatic tissue. A total of 56 female patients w...

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

The dataset represented in this article is referred to by the review article entitled “Topical drug delivery: history, percutaneous absorption, and product development” (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (Jmax)...

Grey matter volume associations with personality functioning in a clinical cohort of female youths

Borderline Personality Disorder (BPD) is a severe mental illness, although its neurobiological underpinnings remain largely unknown. Structural Magnetic Resonance Imaging (sMRI) in adolescents can offer insights into potential biomarkers to...

Corrigendum: Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer

Medical Informatics and Bioinformatics

In the last 50 years, computational applications have been developed to aid clinicians and researchers alike in the broad field of Biomedicine. Adopted early in the evolution of the field, the term medical informatics has been applied to th...

Development and production of an oligonucleotide MuscleChip: use for validation of ambiguous ESTs

Abstract Background We describe the development, validation, and use of a highly redundant 120,000 oligonucleotide microarray (MuscleChip) containing 4,601 probe sets representing 1,150 known genes expressed in muscle and 2,075 EST clusters...

Data for: Terrain units, land use/cover, and gross primary productivity of the largest fluvial basin in the Brazilian Amazonia/Cerrado ecotone: The Araguaia River Basin

Integrity of most of tropical wetlands is threatened because they are often considered freely available resources of land and water. The Araguaia River Basin is one of the Brazilian basins most influenced by tropical seasonal floods, in add...

Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Abstract Background Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the organization of PPI networks is the existence of dense...

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

Postpartum breast cancer (PPBC) - which according to new data, can extend to 5–10 years after the birth - are estimated to represent 35–55% of all cases of breast cancer in women younger than 45 years. Increasing clinical evidence indicates...

Medical Informatics and Bioinformatics: A Bibliometric Study

This paper reports on an analysis of the bioinformatics and medical informatics literature with the objective to identify upcoming trends that are shared among both research fields to derive benefits from potential collaborative initiatives...

The Effects of a Pulmonary Rehabilitation Programme on Functional Capacity and Strength of Respiratory Muscles in Patients with Post-COVID Syndrome

The aim of this study was to estimate the effects of a pulmonary rehabilitation programme (PR) on the functional capacity and respiratory muscle strength of patients with post-COVID syndrome....

Infodemiological data concerning silicosis in the USA in the period 2004–2010 correlating with real-world statistical data

This article reports data concerning silicosis-related web-activities using Google Trends (GT) capturing the Internet behavior in the USA for the period 2004–2010. GT-generated data were then compared with the most recent available epidemio...

A review of medical education and medical informatics

Physicians have considerable difficulty collecting and interpreting information from patients, dealing with the uncertainties associated with diagnosing and treating their patients, communicating precisely with one another, keeping up to da...

Neural substrates of motor and cognitive dysfunctions in SCA2 patients: A network based statistics analysis

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease characterized by a progressive cerebellar syndrome, which can be isolated or associated with extracerebellar signs. It has been shown that patients affe...

Case-based medical informatics

BACKGROUND: The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four ...

On-orbit electrical power system dataset of 1U CubeSat constellation

This article presents a database containing on-orbit data samples of the Electrical Power System (EPS) from 4 different 1U CubeSats belonging to the BIRDS constellation. The EPS is responsible for providing uninterrupted power to overall sa...

Characterization data on the topical carrier DDC642

This article contains original data, figures and methods used in the characterization of the liposomal carrier ‘DDC642’ for topical applications, described in “An elastic liposomal formulation for RNAi-based topical treatment of skin disord...