Academic Articles & Research Papers

A Paradigm for Medical Informatics

Abstract This paper presents a model of the discipline of Medical Informatics. The components of the model are defined and described, and the use of the model in Medical Informatics research, and curriculum development, is discussed....

[Medical informatics].

Medical informatics is the discipline concerned with information and information streams in health care. The development of information technology has been intensified in recent years and is now influencing the international development wit...

Medical Informatics

Information technology has been revolutionizing the everyday life of the common man, while medical science has been making rapid strides in understanding disease mechanisms, developing diagnostic techniques and effecting successful treatmen...

Research in medical informatics

Medical informatics is concerned with the application of computers in the medical and biological sciences and has been considered a field of research in its own right for more than twenty years. In Malaysia, however, there are very few publ...

Medical Informatics

A STUDY ON MEDICAL INFORMATICS

Medical informatics, a rapidly evolving field, plays a pivotal role in improving healthcare delivery, patient outcomes, and the overall healthcare system. This abstract provides an overview of the key concepts, applications, and impacts of ...

Ubiquitous Health and Medical Informatics

Progress in ubiquitous computing, social networking, medical informatics and IT technologies has resulted in a new generation of healthcare systems. This book provides insight into the various trends, innovations, and organizational challen...

Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T

Recent technological progress in the multiband echo planer imaging (MB EPI) technique enables accelerated MR diffusion weighted imaging (DWI) and allows whole brain, multi-b-value diffusion imaging to be acquired within a clinically feasibl...

Non-parametric synergy modeling of chemical compounds with Gaussian processes

Abstract Background Understanding the synergetic and antagonistic effects of combinations of drugs and toxins is vital for many applications, including treatment of multifactorial diseases and ecotoxicological monitoring. Synergy is usually...

Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Abstract Background Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the organization of PPI networks is the existence of dense...

I do not want to suppress the natural process of inflammation: new insights on factors associated with non-adherence in rheumatoid arthritis

Abstract Background It is estimated that 50–70% of patients with rheumatoid arthritis (RA) are non-adherent to their recommended treatment. Non-adherent patients have a higher risk of not reaching an optimal clinical outcome. We explored fa...

Contributions of childhood abuse and neglect to reward neural substrates in adolescence

Background: Childhood adverse experiences may come to bear particularly during adolescence, when neural reward systems are developing rapidly and psychopathology spikes. Despite prior work differentiating threat- (abuse) vs. deprivation- (n...

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

Postpartum breast cancer (PPBC) - which according to new data, can extend to 5–10 years after the birth - are estimated to represent 35–55% of all cases of breast cancer in women younger than 45 years. Increasing clinical evidence indicates...

From BIG Data Center to China National Center for Bioinformation

Rural Telemedicine Use Before and During the COVID-19 Pandemic: Repeated Cross-sectional Study

BackgroundThe COVID-19 pandemic has led to a notable increase in telemedicine adoption. However, the impact of the pandemic on telemedicine use at a population level in rural and remote settings remains unclear. ObjectiveThis st...

Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions

Technology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although singl...

Digital Exclusion and Cognitive Function in Elderly Populations in Developing Countries: Insights Derived From 2 Longitudinal Cohort Studies

BackgroundCognition disorders not only lead to adverse health consequences but also contribute to a range of socioeconomic challenges and diminished capacity for performing routine daily activities. In the digital era, understanding the imp...

Memantine for Refractory Obsessive-Compulsive Disorder: Protocol for a Pragmatic, Double-blind, Randomized, Parallel-Group, Placebo-Controlled, Monocenter Trial

BackgroundObsessive-compulsive disorder (OCD) is a psychiatric syndrome characterized by unwanted and repetitive thoughts and repeated ritualistic compulsions for decreasing distress. Symptoms can cause severe distress and functional impair...

LocateP: Genome-scale subcellular-location predictor for bacterial proteins

Abstract Background In the past decades, various protein subcellular-location (SCL) predictors have been developed. Most of these predictors, like TMHMM 2.0, SignalP 3.0, PrediSi and Phobius, aim at the identification of one or a few SCLs, ...

Performance Evaluation Methods and Suggestions for High-Voltage Generator and Tube of DR System

In the design of DR systems, high-voltage generators and X-ray tubes are two key components whose performance directly affects the system's exposure capabilities. This article first explains why it is necessary to conduct an in-depth evalua...