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Academic Articles & Research Papers
Showing 20 of 197 academic articles
Dylan G. Chitwood, Qinghua Wang, Kathryn Elliott, Aiyana Bullock et al. • BMC Biotechnology
(2021)
Abstract Background As bioprocess intensification has increased over the last 30 years, yields from mammalian cell processes have increased from 10’s of milligrams to over 10’s of grams per liter. Most of these gains in productivity can be ...
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Open Access (DOAJ)
DOI: 10.1186/s12896-020-00667-2
Raphael Charchar Campos Alves, Railson Oliveira Ferreira, Deborah Ribeiro Frazão, Yago Gecy de Souza Né et al. • Antioxidants
(2022)
Salivary content has been reported as a potential biomarker for oxidative stress assessments especially in context of exercise-induced oxidative stress. This systematic review following PRISMA guidelines aimed to evaluate the effects of phy...
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Open Access (DOAJ)
DOI: 10.3390/antiox11081489
Matthew Lynch, Sophie Manoy, Peter D. Sly, Claire E. Wainwright et al. • EBioMedicine
(2025)
Summary: Background: Ataxia-telangiectasia (A-T) is a rare multisystem disease characterised by neurodegenerative cerebellar ataxia, lung disease, immune deficiency, high cancer risk, and mitochondrial dysfunction. A-T cells demonstrate de...
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Open Access (DOAJ)
DOI: 10.1016/j.ebiom.2025.105840
Stewart F. Graham, Nolwen L. Rey, Zafer Ugur, Ali Yilmaz et al. • Metabolites
(2018)
For people with Parkinson’s disease (PD), considered the most common neurodegenerative disease behind Alzheimer’s disease, accurate diagnosis is dependent on many factors; however, misdiagnosis is extremely common in the prodrom...
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Open Access (DOAJ)
DOI: 10.3390/metabo8040071
Yawei Sun, Shuai Wang, Xingwei Zhang, Zhuhao Wu et al. • Biomolecules
(2021)
Background: Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a key enzyme that catalyzes the hydroxylation of lysine, plays a crucial role in the progression of several solid tumors. However, its spatial expression profile and pr...
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Open Access (DOAJ)
DOI: 10.3390/biom11121842
Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology
(2023)
Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...
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Open Access (DOAJ)
DOI: 10.1186/s12957-023-03078-7
Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller et al. • Pathology and Oncology Research
(2025)
ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circ...
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Open Access (DOAJ)
DOI: 10.3389/pore.2024.1611929
Rachel McLatchie, Sarah Wilson, Matthew Reed, Francoise Ticehurst et al. • Emergency Care Journal
(2023)
Objectives: To understand why the diagnosis of AAS is missed in the ED, and to characterise the presenting features of cases in which a diagnosis of AAS was missed.
Methods: A retrospective case series cohort study was performed, identif...
DOAJ
Open Access (DOAJ)
DOI: 10.4081/ecj.2023.11153
Swapno Aditya, Adam Clarke, Lucy Armitage, Wing-Kai Lam et al. • Sensors
(2026)
Background: Age-related changes in motor–cognitive function are associated with altered neural adaptability, particularly during tasks requiring integration of cognitive and motor processes. Dual-task paradigms are commonly used to assess s...
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Open Access (DOAJ)
DOI: 10.3390/s26144575
Windy W. Alonso, Sara E. Bills, Scott W. Lundgren, Steven J. Keteyian et al. • ESC Heart Failure
(2025)
Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF)....
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Open Access (DOAJ)
DOI: 10.1002/ehf2.15341
Liping Sun, Yang Yu, Beifang Niu, Beifang Niu et al. • Frontiers in Genetics
(2020)
The amount of erythrocyte-derived microRNAs (miRNAs) represents the majority of miRNAs expressed in whole blood. miR-451, miR-144, and miR-486, which are abundant in red blood cells (RBCs), are involved in the process of erythropoiesis and ...
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Open Access (DOAJ)
DOI: 10.3389/fgene.2020.00442
Marina M Watowich, Rachel M Petersen, Layla Brassington, Audrey M Arner et al. • PLoS Genetics
(2026)
The apolipoprotein ε4 (APOE ε4) isoform directly alters cholesterol and immune biology and is associated with an increased risk of neurodegenerative and cardiometabolic disease in industrialized settings; nevertheless, APOE ε4-which is ance...
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Open Access (DOAJ)
DOI: 10.1371/journal.pgen.1012285
Noemi Procopio, Caley A. Mein, Sefora Starace, Andrea Bonicelli et al. • Biology
(2021)
The evaluation of bone diagenetic phenomena in archaeological timescales has a long history; however, little is known about the origins of the microbes driving bone diagenesis, nor about the extent of bone diagenesis in short timeframes—suc...
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Open Access (DOAJ)
DOI: 10.3390/biology10060460
Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology
(2021)
Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...
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Open Access (DOAJ)
DOI: 10.1186/s13000-021-01127-x
Anca Otilia Farcas, Mihai Ciprian Stoica, Septimiu Voidazan, Carmen Corina Radu et al. • Diagnostics
(2026)
Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...
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Open Access (DOAJ)
DOI: 10.3390/diagnostics16152432
Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals
(2025)
Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...
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Open Access (DOAJ)
DOI: 10.3390/ph18081111
Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes
(2024)
Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...
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Open Access (DOAJ)
DOI: 10.3390/fishes9020076
S. Y. Al-Okbi, D. A. Mohamed, E. Kandil, M. A. Abo-Zeid et al. • Grasas y Aceites
(2017)
The aim of the present research was to evaluate the anti-inflammatory activity of pumpkin seed oils (PSOs) of an Egyptian and European variety, in a rat model of adjuvant arthritis. Edema thickness, plasma tumor necrosis factor-α (TNF-α) an...
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Open Access (DOAJ)
DOI: 10.3989/gya.0796161
Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine
(2023)
BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...
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Open Access (DOAJ)
DOI: 10.3389/fmed.2022.1034290
Wenchao Yu, Wenchao Yu, Yisha Lu, Yisha Lu et al. • Frontiers in Microbiology
(2022)
Feed efficiency (FE) is critical to the economic and environmental benefits of aquaculture. Both the intestines and intestinal microbiota play a key role in energy acquisition and influence FE. In the current research, intestinal microbiota...
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Open Access (DOAJ)
DOI: 10.3389/fmicb.2022.852460