Reset
Showing 20 of 3,721 academic articles

Systematic evolution of bZIP transcription factors in Malvales and functional exploration of AsbZIP14 and AsbZIP41 in Aquilaria sinensis

Hao Zhang, Xupo Ding, Xupo Ding, Hao Wang et al. • Frontiers in Plant Science (2023)

IntroductionAgarwood, the dark-brown resin produced by Aquilaria trees, has been widely used as incense, spice, perfume or traditional medicine and 2-(2-phenethyl) chromones (PECs) are the key markers responsible for agarwood formation. But...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpls.2023.1243323

MRI Application in Quantification of Epiphyseal Development in the Wrist and Bone Age Estimation of Han Male Adolescents in East China

ZHOU Zhi-lu, ZHANG Dong-fei, CHEN Jie-min, WANG Ya-hui et al. • Fayixue Zazhi (2024)

ObjectiveTo investigate the value of wrist MRI in bone age estimation for male adolescents in Shanghai, Zhejiang and Jiangsu.MethodsA total of 124 Han male adolescents aged 6.0 to 18.0 years from Shanghai, Zhejiang and Jiangsu were selected...

DOAJ Open Access (DOAJ) DOI: 10.12116/j.issn.1004-5619.2023.231203

Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry

SHI Hong-fei1, XU Bo-peng1, QUAN Yang-ke2, XU Cheng-xin1, ZHOU Xiu-qi1 • Zhipu Xuebao (2024)

Khat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar. However, some studies showed that there are differences in the intensi...

DOAJ Open Access (DOAJ) DOI: 10.7538/zpxb.2023.0065

A Coarse-to-Fine Approach for Rectifying Distorted Latent Fingerprints From Crime Scenes

Qing Bao, Ya-Gang Wang, Chang Gao, Liangxiao Sha et al. • IEEE Access (2023)

With the widely used fingerprints to identify criminals, the influence of fingerprint deformation arouses attention in forensic science. To date, many approaches have been proposed to rectify distorted fingerprints. However, the performance...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2023.3344465

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Anca Otilia Farcas, Mihai Ciprian Stoica, Septimiu Voidazan, Carmen Corina Radu et al. • Diagnostics (2026)

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16152432

Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Marker

YANG Yue , TAO Rui-yang , LI Min , et al. • Fayixue Zazhi (2021)

The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, ...

DOAJ Open Access (DOAJ) DOI: 10.12116/j.issn.1004-5619.2020.501205

Bacterial Succession in Microbial Biofilm as a Potential Indicator for Postmortem Submersion Interval Estimation

Finkelbergs Dmitrijs, Juanjuan Guo, Juanjuan Guo, Juanjuan Guo et al. • Frontiers in Microbiology (2022)

Bacteria acts as the main decomposer during the process of biodegradation by microbial communities in the ecosystem. Numerous studies have revealed the bacterial succession patterns during carcass decomposition in the terrestrial setting. T...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.951707

A pilot study of mitochondrial genomic ancestry in admixed Brazilian patients with type 1 diabetes

Lívia Leite Ferreira, Anna Beatriz Rodrigues Gonçalves, Igor Josué Barbosa Adiala, Silvia Loiola et al. • Diabetology & Metabolic Syndrome (2024)

Abstract Interactions between multiple genes and environmental factors could be related to the pathogenesis of type 1 diabetes (T1D). The Brazilian population results from different historical miscegenation events, resulting in a highly div...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13098-024-01342-8

Optimization of Bacillus cereus Fermentation Process for Selenium Enrichment as Organic Selenium Source

Xujun Chen, Shuyi Li, Xin Cong, Xin Cong et al. • Frontiers in Nutrition (2020)

Selenium is an essential trace element and micronutrient for human health. Application of organic selenium in plants and microorganisms as trace element supplement is attracting more and more attention. In this study, Bacillus cereus, an im...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2020.543873

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports (2020)

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2020.04.011

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals (2025)

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph18081111

The features analysis of hemoglobin expression on visual information transmission pathway in early stage of Alzheimer’s disease

Xuehui Li, Pan Tang, Xinping Pang, Xianghu Song et al. • Scientific Reports (2024)

Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized primarily by cognitive impairment. The motivation of this paper is to explore the impact of the visual information transmission pathway (V–H pathway) on AD, and...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-64099-0

Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review

Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino et al. • International Journal for Equity in Health (2025)

Abstract Introduction Humanitarian crises exacerbate the vulnerability of already fragile healthcare systems and significantly increase the risk of infectious disease outbreaks in low- and middle-income countries (LMICs). This systematic re...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-025-02382-w

Impact of Pressurized Liquid Extraction and pH on Protein Yield, Changes in Molecular Size Distribution and Antioxidant Compounds Recovery from Spirulina

Jianjun Zhou, Min Wang, Celia Carrillo, Zhenzhou Zhu et al. • Foods (2021)

The research aims to extract nutrients and bioactive compounds from spirulina using a non-toxic, environmentally friendly and efficient method—Pressurized Liquid Extraction (PLE). In this work, Response Surface Methodology (RSM)–Central Com...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10092153

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

Xinyi Wei, Yanding Su, Qian Cheng, Songmao Liang et al. • Frontiers in Pharmacology (2024)

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beag...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2024.1334402

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

Diletta Fontana, Mario Mauri, Rossella Renso, Mattia Docci et al. • Nature Communications (2020)

ETNK1 mutations are recurrent in leukemia but how they contribute to oncogenesis is still unclear. Here, the authors show that ETNK1 mutations increase mitochondrial activity, ROS and H2AX levels and that these effects can be rescued upon p...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-020-19721-w