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Academic Articles & Research Papers
Showing 20 of 23,220 academic articles
Camila Fabiani, Camila Fabiani, Silvia S. Antollini, Silvia S. Antollini • Frontiers in Cellular Neuroscience
(2019)
Biological membranes show lateral and transverse asymmetric lipid distribution. Cholesterol (Chol) localizes in both hemilayers, but in the external one it is mostly condensed in lipid-ordered microdomains (raft domains), together with satu...
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Open Access (DOAJ)
DOI: 10.3389/fncel.2019.00309
S. Vasanthakumar, M. Manikandan, Muthu Arumugam • Biochemistry and Biophysics Reports
(2024)
Selenium, an essential micronutrient with potent anticancer and antioxidant properties, the inorganic form of selenium is highly toxic, while organic and elemental nanoforms are more bioavailable and less toxic and have gained attention owi...
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Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2024.101760
Evan J Worden, Xiangbin Zhang, Cynthia Wolberger • eLife
(2020)
Methylation of histone H3K4 is a hallmark of actively transcribed genes that depends on mono-ubiquitination of histone H2B (H2B-Ub). H3K4 methylation in yeast is catalyzed by Set1, the methyltransferase subunit of COMPASS. We report here th...
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Open Access (DOAJ)
DOI: 10.7554/eLife.53199
Amedeo Balbi, Claudio Grimaldi • The Astronomical Journal
(2024)
The probability of detecting technosignatures (i.e., evidence of technological activity beyond Earth) increases with their longevity, or the time interval over which they manifest. Therefore, the assumed distribution of longevities has some...
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Open Access (DOAJ)
DOI: 10.3847/1538-3881/ad217d
Yuxiong Lu, Junichi Maruyama, Keiko Kuwata, Hiroyuki Fukuda et al. • Biochemistry and Biophysics Reports
(2018)
Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer st...
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Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2018.10.014
Dipsikha Biswas, Logan Slade, Luke Duffley, Neil Mueller et al. • Cell Death Discovery
(2021)
Proposed mechanism. A Doxorubicin (DOX) targets the BCAA catabolic pathway in TNBCs, by downregulating BCKDK and augmenting clearance of intracellular BCKAs. B Genetic or pharmacological (high BT2 concentration) inhibition of BCKDK results ...
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Open Access (DOAJ)
DOI: 10.1038/s41420-021-00602-0
Dimitri Vanhecke, Dagmar A. Kuhn, Dorleta Jimenez de Aberasturi, Sandor Balog et al. • Beilstein Journal of Nanotechnology
(2017)
Little is known about the simultaneous uptake of different engineered nanoparticle types, as it can be expected in our daily life. In order to test such co-exposure effects, murine macrophages (J774A.1 cell line) were incubated with gold (A...
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Open Access (DOAJ)
DOI: 10.3762/bjnano.8.239
Zvereva Elvira, Makarova Anastasiya, Ilyin Nikolay, Ageeva Marina et al. • E3S Web of Conferences
(2023)
The possibility of reuse of heavy residues (oily sludge) of low-sulfur, highly paraffinic Mangyshlak oils as a basis for fuel with improved environmental characteristics for engines to marine, river and railway transport, gas turbine and bo...
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Open Access (DOAJ)
DOI: 10.1051/e3sconf/202337604020
Alexandra Kühnlein, Simon A Lanzmich, Dieter Braun • eLife
(2021)
Can replication and translation emerge in a single mechanism via self-assembly? The key molecule, transfer RNA (tRNA), is one of the most ancient molecules and contains the genetic code. Our experiments show how a pool of oligonucleotides, ...
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Open Access (DOAJ)
DOI: 10.7554/eLife.63431
Sai Shashank Chavali, Steven Z. Chou, Wenxiang Cao, Thomas D. Pollard et al. • Nature Communications
(2024)
Abstract Arp2/3 complex nucleates branched actin filaments for cell and organelle movements. Here we report a 2.7 Å resolution cryo-EM structure of the mature branch junction formed by S. pombe Arp2/3 complex that provides details about int...
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Open Access (DOAJ)
DOI: 10.1038/s41467-024-46179-x
Lucas Rodrigues Moraes, Pedro Leme Silva, Denise Battaglini, Patricia Rieken Macedo Rocco • Medicina
(2026)
Acute respiratory distress syndrome (ARDS) is a heterogeneous inflammatory lung injury marked by increased alveolar–capillary permeability, reduced respiratory system compliance, and impaired gas exchange. Despite advances in supportive car...
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Open Access (DOAJ)
DOI: 10.3390/medicina62020420
Nobuhiko Kajinami, Mitsuhiro Matsumoto • Biophysics and Physicobiology
(2019)
Human knee joints move smoothly under high load conditions due to articular cartilage and synovial fluid. Much attention is paid to the role of proteoglycans. It is suggested that a part of proteoglycan forms aggregate on the cartilage surf...
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Open Access (DOAJ)
DOI: 10.2142/biophysico.16.0_466
Qinghua Luo, Xintan Dong, Zhaxi Zerang, Yujiao Chen et al. • Cell Reports
(2026)
Summary: The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and...
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Open Access (DOAJ)
DOI: 10.1016/j.celrep.2026.117733
Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky et al. • MicrobiologyOpen
(2026)
ABSTRACT The ability of gut microbes to degrade host‐ and diet‐derived glycans is central to microbiome ecology and host interactions, yet predicting these functions in silico remains challenging. Hyaluronan (HA), a glycosaminoglycan (GAG) ...
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Open Access (DOAJ)
DOI: 10.1002/mbo3.70227
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder et al. • Scientific Reports
(2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo ...
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Open Access (DOAJ)
DOI: 10.1038/s41598-022-10119-w
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology
(2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....
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Open Access (DOAJ)
DOI: 10.1038/s42003-022-03753-7
Veronika Heinz, Wenke Jäckel, Susann Kaltwasser, Laura Cutugno et al. • Communications Biology
(2022)
A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the respon...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-022-03548-w
Maral Rahimzadeh, Majid Sadeghizadeh, Farhood Najafi, Seyed Shahriar Arab et al. • Materials Research Express
(2020)
During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...
DOAJ
Open Access (DOAJ)
DOI: 10.1088/2053-1591/ab770f
Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine
(2017)
Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...
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Open Access (DOAJ)
DOI: 10.20892/j.issn.2095-3941.2016.0086
Fernanda Bajanca, Nadège Gouignard, Charlotte Colle, Maddy Parsons et al. • Nature Communications
(2019)
Migrating cells encounter multiple signals such as extracellular matrix (ECM) and chemokinetic factors but how these integrate in vivo is unclear. Here, the authors report that overall control of cell-ECM adhesion by Sema3A and Sdf1 can be ...
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Open Access (DOAJ)
DOI: 10.1038/s41467-019-09548-5