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Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy

O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика (2025)

Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...

DOAJ Open Access (DOAJ) DOI: 10.17749/2070-4909/farmakoekonomika.2024.285

Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory

Suhel Tamboli, Sanjay Singh, Dimitry Topolnik, Mohamed El Amine Barkat et al. • Cell Reports (2024)

Summary: In the CA1 hippocampus, vasoactive intestinal polypeptide-expressing interneurons (VIP-INs) play a prominent role in disinhibitory circuit motifs. However, the specific behavioral conditions that lead to circuit disinhibition remai...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2024.114115

Investigating the performance of the fluorescent sensor g-C3N4/Fe/Cu in detecting the Tenofovir drug

Nafiseh Hajian Afarani, Fatemeh Keshavarzi, Kahin Shahanipour, Seyed Amir Zarei • Scientific Reports (2025)

Abstract Tenofovir is an antiviral drug that prevents the replication of AIDS and hepatitis B viruses. To minimize the harmful side effects of the drug on the body, it is essential to determine its precise concentration in the blood. Fluore...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-08877-4

Sequential Portal Vein Embolization and Percutaneous Radiofrequency Ablation for Future Liver Remnant Growth: A Minimally Invasive Alternative to ALPPS Stage-1 in Treatment of Hepatocellular Carcinoma

Qiang Wang, Qiang Wang, Yujun Ji, Torkel B. Brismar et al. • Frontiers in Surgery (2021)

Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for stage...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsurg.2021.741352

Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults

Müjgan Ercan, Emiş Deniz Akbulut, Ayşen Caniklioğlu, Esra Fırat Oğuz et al. • Journal of Mass Spectrometry and Advances in the Clinical Lab (2025)

Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jmsacl.2025.04.010

Evaluation of Lipid Profile and Inflammatory Marker in Patients with Gastric Helicobacter pylori Infection, Ethiopia

Temesgen GB, Menon M, Gizaw ST, Yimenu BW et al. • International Journal of General Medicine (2022)

Gelagey Baye Temesgen,1 Menakath Menon,2 Solomon Tebeje Gizaw,2 Bayu Wondimneh Yimenu,1 Melaku Mekonen Agidew3 1Department of Biomedical Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Medical Biochemistry School o...

DOAJ Open Access (DOAJ)

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Impact of Myocardial Ischemia and Revascularization by Percutaneous Coronary Intervention on Circulating Level of Soluble ST2

Alkhateeb A, Mahmoud HEM, AK M, Hassan MH et al. • Vascular Health and Risk Management (2023)

Areej Alkhateeb,1 Hossam Eldin M Mahmoud,1 Mohammed AK,1 Mohammed H Hassan,2 Abdel Rahim Mahmoud Muddathir,3 Ahmed G Bakry1 1Cardiology Division of Internal Medicine Department, South Valley University Hospital, Faculty of Medicine, South V...

DOAJ Open Access (DOAJ)

Synthesis of 9-arylalkynyl- and 9-aryl-substituted benzo[b]quinolizinium derivatives by Palladium-mediated cross-coupling reactions

Siva Sankar Murthy Bandaru, Darinka Dzubiel, Heiko Ihmels, Mohebodin Karbasiyoun et al. • Beilstein Journal of Organic Chemistry (2018)

9-Arylbenzo[b]quinolizinium derivatives were prepared with base-free Suzuki–Miyaura coupling reactions between benzo[b]quinolizinium-9-trifluoroborate and selected benzenediazonium salts. In addition, the Sonogashira coupling reaction betwe...

DOAJ Open Access (DOAJ) DOI: 10.3762/bjoc.14.161

Synthesis and properties of fluorene based small molecule acceptors containing aromatic malononitrile functionalities

Sarah E. Brock, Dariia Yehorova, Brycelyn M. Boardman • Results in Chemistry (2022)

Four novel small molecule acceptors (SMA) with fluorene-based cores were synthesized with terminal phenyl, thienyl, and furyl malononitrile groups in good yields. The products were obtained from a two-step reaction of 2,2′-(9,9-dioctyl-9H-f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2022.100320

Water and soil pollution as determinant of water and food quality/contamination and its impact on female fertility

Justin Rashtian, Diana E. Chavkin, Zaher Merhi • Reproductive Biology and Endocrinology (2019)

Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse repr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12958-018-0448-5

Review on: Women with Polycystic Ovary Syndrome

Neelam Gusain, Ashish P. Anjankar, Ranjit S. Ambad, Roshan K. Jha et al. • Journal of Pharmacy and Bioallied Sciences (2025)

One of the biggest health issues facing women in their childbearing years worldwide is polycystic ovarian syndrome, or PCOS. PCOS is a prevalent endocrine condition with well-known negative effects on metabolism, reproduction, and cardiovas...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.jpbs_1995_24

Ozonation, electrochemical, and biological methods for the remediation of malachite green dye wastewaters: A mini review

Peter Olusakin Oladoye, Timothy Oladiran Ajiboye, Wycliffe Chisutia Wanyonyi, Elizabeth Oyinkansola Omotola et al. • Sustainable Chemistry for the Environment (2023)

The extensive usage of malachite green (MG) dyes in the fish and dye industries cause serious water pollution, leading to catastrophic effects on living organisms and the environment. In addressing the challenges of health risks related to ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.scenv.2023.100033

CCR4, a RNA decay factor, is hijacked by a plant cytorhabdovirus phosphoprotein to facilitate virus replication

Zhen-Jia Zhang, Qiang Gao, Xiao-Dong Fang, Zhi-Hang Ding et al. • eLife (2020)

Carbon catabolite repression 4 (CCR4) is a conserved mRNA deadenylase regulating posttranscriptional gene expression. However, regulation of CCR4 in virus infections is less understood. Here, we characterized a pro-viral role of CCR4 in rep...

DOAJ Open Access (DOAJ) DOI: 10.7554/eLife.53753

Untargeted metabolomic profiling of Pseudocnella sykion from KwaZulu-Natal, South Africa using 1H-NMR and UPLC-QTOF-HR-MS

Cassandra Upton, Gerhard Prinsloo, Paul Anton Steenkamp, Moses Okpeku • Frontiers in Marine Science (2025)

IntroductionSea cucumbers are ecologically and economically significant marine invertebrates, yet the metabolic diversity and bioactive potential of noncommercialized, endemic species remains poorly understood.MethodsThis study presents the...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2025.1609951

Evaluation of Population and Hybrid Varieties of Winter Rye in the Conditions of Eastern Siberia

Anatolii V. Pomortsev, Nikolay V. Dorofeev, Svetlana Yu. Zorina, Natalia B. Katysheva et al. • Agronomy (2023)

Winter rye has a high adaptive capacity to abiotic and biotic stressors compared to other winter crops (wheat, triticale, barley, and oats). High resistance of winter rye to adverse environmental factors and a wide range of its uses increas...

DOAJ Open Access (DOAJ) DOI: 10.3390/agronomy13051431

Brassinosteroid-lipid membrane interaction under low and high temperature stress in model systems

Elżbieta Rudolphi-Szydło, Barbara Dyba, Anna Janeczko, Dariusz Latowski et al. • BMC Plant Biology (2022)

Abstract Background In earlier studies [1], we indicated that applying brassinosteroids (BRs) to lipids that had been isolated from plants altered the physicochemical properties of the monolayers. A continuation of these dependencies using ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12870-022-03619-4

The Relationship between Exercise and Salivary Oxidative Stress: A Systematic Review

Raphael Charchar Campos Alves, Railson Oliveira Ferreira, Deborah Ribeiro Frazão, Yago Gecy de Souza Né et al. • Antioxidants (2022)

Salivary content has been reported as a potential biomarker for oxidative stress assessments especially in context of exercise-induced oxidative stress. This systematic review following PRISMA guidelines aimed to evaluate the effects of phy...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11081489