Academic Articles & Research Papers

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

Multidetector Computed Tomography (MDCT) Findings of Complications of Acute Cholecystitis. A Pictorial Essay

Acute cholecystitis stands out as one of the most common surgical pathologies that should always be considered in a right-upper abdominal pain emergency. For this, the importance of a correct diagnosis is well described. However, it has bee...

Is telemedicine a subset of medical informatics?

Informatics has a key characteristic of a new discipline in a technically transient environment--there is no universal definition of it. This is not surprising, given its complex and diverse nature. In a broad sense informatics is the inter...

Evolution of medical informatics in bibliographic databases

Medical informatics became a medical specialty during the last years and this is evidenced by a great amount of journal articles regarding the subject published worldwide. We compared the presentation of Medical Informatics in two different...

Impacts of the COVID-19 Pandemic on Primary Care Utilization: An Analysis of Primary Care Claims Data in Alberta, Canada

Background: The COVID-19 pandemic disrupted primary health care systems worldwide, prompting rapid changes in how care was delivered. In Alberta, this included a significant shift from in-person to virtual care. This study examines trends i...

Medical Informatics in Medical Research

OBJECTIVES: Computers are widely used for data management in clinical trials in the developed countries, unlike in developing countries. Dependable systems are vital for data management, and medical decision making in clinical research. Mon...

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

Abstract Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening. While MRI is the principal tool available to neurologis...

Income and education predict elevated depressive symptoms in the general population: results from the Gutenberg health study

Abstract Background Socioeconomic status (SES) has a strong association with depression or physical and mental health in general. However, as SES is a multifaceted construct these associations are not easy to explain. Further, there are sev...

Datasets associated with investigating the potential for beneficial reuse of produced water from oil and gas extraction outside of the energy sector

The data in this report are associated with https://doi.org/10.1016/j.scitotenv.2020.137085 [4] and include data on water volumes and water quality related to the major unconventional oil and gas plays in the U.S. The data include volumes o...

Is a prostate cancer screening anxiety measure invariant across two different samples of age-appropriate men?

Abstract Background In order to explore the influence of anxiety on decision–making processes, valid anxiety measures are needed. We evaluated a prostate cancer screening (PCS) anxiety scale that measures anxiety related to the prostate–spe...

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

The dataset represented in this article is referred to by the review article entitled “Topical drug delivery: history, percutaneous absorption, and product development” (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (Jmax)...

Adherence to Blended or Face-to-Face Smoking Cessation Treatment and Predictors of Adherence: Randomized Controlled Trial

BackgroundBlended face-to-face and web-based treatment is a promising way to deliver smoking cessation treatment. Since adherence has been shown to be an indicator of treatment acceptability and a determinant for effectiveness, we explored ...

Antecedents of the People and Organizational Aspects of Medical Informatics: Review of the Literature

People and organizational issues are critical in both implementing medical informatics systems and in dealing with the altered organizations that new systems often create. The people and organizational issues area--like medical informatics ...

HRI-confusion: A multimodal dataset for modelling and detecting user confusion in situated human-robot interaction

The dataset was collected from 28 participants (17 female, 9 male, and 1 non-binary) for a study aimed at modelling and detecting user social behaviours with different confusion states in task-oriented situated human-robot interaction (HRI)...

A review of medical education and medical informatics

Physicians have considerable difficulty collecting and interpreting information from patients, dealing with the uncertainties associated with diagnosing and treating their patients, communicating precisely with one another, keeping up to da...

Medical Informatics

Sex-specific frontal-striatal connectivity differences among adolescents with externalizing disorders

Background: Sex-specific neurobiological underpinnings of impulsivity in youth with externalizing disorders have not been well studied. The only report of functional connectivity (FC) findings in this area demonstrated sex differences in fr...

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia

The role of subclonal TP53 mutations, defined by a variant allele frequency of 40%, 20%-40% and 40%, 19 had variant allele frequencies between 20%-40% and 18 had frequencies...

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

Characterization data on the topical carrier DDC642

This article contains original data, figures and methods used in the characterization of the liposomal carrier ‘DDC642’ for topical applications, described in “An elastic liposomal formulation for RNAi-based topical treatment of skin disord...