Academic Articles & Research Papers

Regulatory challenges and current policy for cardiotoxicity detection in oncology drug development.

Association Between DPYD Gene Variants and Severe Fluoropyrimidine-Related Toxicity in Asian and African Populations: A Systematic Review.

Human Toxicity and Marine Ecotoxicological Risk of Methanol as a Ship Fuel: A Critical Narrative Review of Exposure, Fate and Aquatic Effects.

Antimicrobial, Anti-Inflammatory, General Toxicity and Antioxidant Activities of Ultrasound-Assisted Extracts from Prunella vulgaris L.

Immunoinformatics and Reverse Vaccinology Approach for the Identification of Potential Vaccine Candidates against <i>Vandammella animalimors</i>

Vandammella animalimorsus is a Gram-negative and non-motile bacterium typically transmitted to humans through direct contact with the saliva of infected animals, primarily through biting, scratches, or licks on fractured skin. The absence o...

Functionalization of polyoxometalates: towards advanced applications in catalysis and materials science

Functionalization via covalent grafting of organic functions allows to tune the redox and acid-base properties, and the solubility of polyoxometalates, to enhance their stability and biological activity and to reduce their toxicity, to faci...

Review on nanocomposite materials from cellulose, chitosan, alginate, and lignin for removal and recovery of nutrients from wastewater

Nutrient enrichment of the aquatic system promotes eutrophication, which degrades the aesthetic and economic value of water systems. On the other hand, the global supply of nutrients such as phosphate is dwindling. Hence, from the viewpoint...

Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility through discrepant atomic interaction

Recent advancement in nanotechnology seeks exploration of new techniques for improvement in the molecular, chemical, and biological properties of nanoparticles. In this study, carbon modification of octahedral-shaped magnetic nanoparticles ...

ProLonged Liposomal Delivery of TLR7/8 Agonist for Enhanced Cancer Vaccine

Despite numerous studies on cancer treatment, cancer remains a challenging disease to cure, even after decades of research. In recent years, the cancer vaccine has emerged as a promising approach for cancer treatment, offering few unexpecte...

Nanotechnology for parasitic plant control

The field of nanotechnology opens up novel potential applications for agriculture. Nanotechnology applications are already being explored and used in medicine and pharmacology, but interest for use in crop protection is just starting. The d...

Nanotechnology for cancer treatment

Nanotechnology has the potential to increase the selectivity and potency of chemical, physical, and biological approaches for eliciting cancer cell death while minimizing collateral toxicity to nonmalignant cells. Materials on the nanoscale...

Nanotechnology for Plant Disease Management

Each year, 20%–40% of crops are lost due to plant pests and pathogens. Existing plant disease management relies predominantly on toxic pesticides that are potentially harmful to humans and the environment. Nanotechnology can offer advantage...

A review on nanofertilizers: Advancements, applications, and implications for agricultural sustainability

Nanofertilizers are a new approach to modern agriculture through specific and effective delivery of nutrients through nanoscale engineering. In comparison to conventional fertilizers, nanofertilizers offer higher nutrient use efficiency, pr...

Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose...

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Ja...

Nanotechnology in Textiles

Increasing customer demand for durable and functional apparel manufactured in a sustainable manner has created an opportunity for nanomaterials to be integrated into textile substrates. Nanomoieties can induce stain repellence, wrinkle-free...

Environmental Risks of Nanotechnology: National Nanotechnology Initiative Funding, 2000−2004

By considering risk in the early stages of a technology, costs of identifying important health and environmental impacts after a technology has widely diffused can be avoided. Nanotechnology, involving materials and objects less than 100 nm...

Weed Management by In Situ Cover Crops and Anaerobic Soil Disinfestation in Plasticulture

Weeds negatively affect organic vegetable crop growth and profitability. Weed management is the greatest challenge for vegetable organic growers since control options are limited for organic vegetable production. Anaerobic soil disinfestati...

Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review

The reuterin system is a complex multi-component antimicrobial system produced by Limosilactobacillus reuteri by metabolizing glycerol. The system mainly includes 3-hydroxypropionaldehyde (3-HPA, reuterin), 3-HPA dimer, 3-HPA hydrate, acrol...

Generation of proximal tubule spheroids for nephrotoxicity assessment

Background To date, nephrotoxicity in new drug development has been evaluated through two-dimensional culture of representative cell lines, such as HK-2 and human proximal tubule epithelial cells (hPTECs). Approximately 20% of new drugs tha...