Reset
Showing 20 of 65 academic articles

Diffuse hypertrophic obstructive cardiomyopathy complicated by apical ventricular aneurysm and excessive left ventricular trabeculation: a case report

Ying Li, Ying Li, Na Jia, Xinyue Li et al. • Frontiers in Cardiovascular Medicine (2026)

This article reports a rare case of diffuse hypertrophic obstructive cardiomyopathy complicated with left ventricular apical aneurysm and excessive trabeculation. Genetic testing of the patient revealed a heterozygous variant of the MYBPC3 ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2026.1753832

Healthy lifestyle attenuates the clonal hematopoiesis-associated coronary artery disease risk

Yuxin Yang, Xuxiang Shen, Keyong Huang, Hongwei Liu et al. • Fundamental Research (2026)

Lifestyle factors and clonal hematopoiesis of indeterminate potential (CHIP) both contribute to the risk of developing coronary artery disease (CAD), but whether a healthy lifestyle could attenuate CHIP-related CAD risk is unknown. A total ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fmre.2025.09.012

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Xiaohang Yang, Jingjing Yin, Yu Fu, Yuanming Shen et al. • Diagnostic Pathology (2023)

Abstract Introduction Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stag...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-023-01294-z

Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence

Xiaojie Huang, Xinchao Liu, Jieqing Chen, Yugang Bao et al. • Frontiers in Immunology (2018)

BackgroundWestern blot (WB) assay is considered the gold standard test for HIV infection confirmation. However, it requires technical expertise and is quite time-consuming. WHO recommends blood-based rapid diagnosis to achieve same-day test...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2018.01458

Analysis of TORCH screening and prenatal risk assessment for childbearing-age women in different regions of China

Yuan Zhang, Ya Zhang, Jing Wang, Li Lin et al. • Journal of Health, Population and Nutrition (2025)

Abstract Objective By conducting TORCH screening and risk assessment analysis on childbearing-age women in different regions of China, the aim is to provide reference for reducing adverse pregnancy outcomes and improving the health status o...

DOAJ Open Access (DOAJ) DOI: 10.1186/s41043-025-01084-x

Preferences for and drivers of adult vaccination clinic site selection: A cross-sectional study in 30 provinces in China

Yuxi Liu, Yanlin Cao, Yugang Li, Siyuan Liu et al. • Human Vaccines & Immunotherapeutics (2025)

Focusing on vaccines available to adults and not in the immunization schedule, this study investigates the preferences and factors influencing adults in selecting vaccination clinic locations. It aims to provide strategic insights for boost...

DOAJ Open Access (DOAJ) DOI: 10.1080/21645515.2024.2442104

Changes in the nonlinear and viscoelastic mechanical properties of the rat lamina cribrosa under chronic high intraocular pressure

Yuqing Wang, Liu Liu, Liu Liu, Jingxi Zhang et al. • Frontiers in Bioengineering and Biotechnology (2026)

IntroductionThe lamina cribrosa (LC) in the optic nerve head is the initial site of glaucomatous optic nerve injury. Under high intraocular pressure (IOP), the deformation of the LC compresses the retinal ganglion cell (RGC) axons passing t...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2026.1875609

A systematic review of the impact of master's-educated nurses on inpatient care

Song Ge, Xing Xi, Gui-fang Guo • International Journal of Nursing Sciences (2015)

Aim: Review the impact of master's-educated nurses on inpatient care in different healthcare systems and specialties. Background: Improved healthcare service quality and efficiency are needed due to a number of factors, including an aging p...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijnss.2015.10.003

Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Jing Jin, Yun Wang, Sixiang Liang, Qingchen Fan et al. • NeuroImage: Clinical (2025)

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2025.103902

Health-related quality of life in Chinese population with non-alcoholic fatty liver disease: a national multicenter survey

Rui Huang, Jian-Gao Fan, Jun-Ping Shi, Yi-Min Mao et al. • Health and Quality of Life Outcomes (2021)

Abstract Background Health Related Quality of Life (HRQL) is a multi-dimensional construct that can comprehensively evaluate the patient’s health status, including physical, emotional, mental and social well-being. In this study, we aimed t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-021-01778-w

The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis

Jiayue Guo, MPH, Lili You, PhD, Lu Liu, MPH, Xitong Jiao, MPH et al. • Mayo Clinic Proceedings: Digital Health (2026)

Objective: To summarize the key intervention characteristics and evaluate the effectiveness and safety of digital therapeutics (DTx) in patients receiving oral anticoagulation, with effectiveness evaluated using time in therapeutic range (T...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.mcpdig.2026.100336

Electronic symptom monitoring of patient-reported outcomes among patients with hepatocellular carcinoma during immunotherapy (PRIME-HCC): protocol for a randomised controlled trial

Yanshang Wang, Xiaoping Wei • BMJ Open (2026)

Introduction Electronic patient-reported outcome (ePROs)-based symptom monitoring benefits health-related quality of life (HRQoL) in various cancers. However, despite the high disease and economic burden of hepatocellular carcinoma (HCC) an...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2026-116199

Soil Geochemical Properties Influencing the Diversity of Bacteria and Archaea in Soils of the Kitezh Lake Area, Antarctica

Qinxin Li, Nengfei Wang, Wenbing Han, Botao Zhang et al. • Biology (2022)

It is believed that polar regions are influenced by global warming more significantly, and because polar regions are less affected by human activities, they have certain reference values for future predictions. This study aimed to investiga...

DOAJ Open Access (DOAJ) DOI: 10.3390/biology11121855

High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa

Yan Yang, Xue Li, Lang Sun, Xiu-Kun Wang et al. • Microbiology Spectrum (2025)

ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global threat, but the mechanism of non-carbapenemase carbapenem resistance is still unclear. In the current study, we investigated the contributions of point mutations in mex...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.01398-24

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450