Academic Articles & Research Papers

Hypertension and medical informatics.

BACKGROUND: Only about 27% of Americans with hypertension have their disease under control. Hypertension in the African-American population has a higher prevalence (32%) and is less likely to be treated or controlled compared with that in t...

The Structure of Medical Informatics Journal Literature

OBJECTIVE: Medical informatics is an emergent interdisciplinary field described as drawing upon and contributing to both the health sciences and information sciences. The authors elucidate the disciplinary nature and internal structure of t...

Science and Practice: A Case for Medical Informatics as a Local Science of Design

Because scientific research is guided by concerns for uncovering "fundamental truths," its time frame differs from that of design, development, and practice, which are driven by immediate needs for practical solutions. In medicine, however,...

Psychometric analysis of the questionnaires for the assessment of upper limbs available in their Italian version: a systematic review of the structural and psychometric characteristics

Abstract Introduction There is no systematic review that analyzes the psychometric properties of questionnaires in Italian. Previous studies have analyzed the psychometric characteristics of instruments for the measurement of pathologies of...

Neural substrates of motor and cognitive dysfunctions in SCA2 patients: A network based statistics analysis

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease characterized by a progressive cerebellar syndrome, which can be isolated or associated with extracerebellar signs. It has been shown that patients affe...

Sex-specific frontal-striatal connectivity differences among adolescents with externalizing disorders

Background: Sex-specific neurobiological underpinnings of impulsivity in youth with externalizing disorders have not been well studied. The only report of functional connectivity (FC) findings in this area demonstrated sex differences in fr...

The relationship between informatics competency and clinical competency in nurses working in intensive care units: A Cross-sectional Study in Northeast Iran

Background: The use of information technology improves the competency of nurses at the bedside. This study was conducted to determine the relationship between informatics competency and clinical competency in nurses working in intensive car...

Case-based medical informatics

BACKGROUND: The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four ...

Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey

Abstract Background The COVID-19 pandemic restrictions posed challenges to maintaining healthy lifestyles and physical well-being. During the first mobility restrictions from March to mid-July 2020, the German population was advised to stay...

On-orbit electrical power system dataset of 1U CubeSat constellation

This article presents a database containing on-orbit data samples of the Electrical Power System (EPS) from 4 different 1U CubeSats belonging to the BIRDS constellation. The EPS is responsible for providing uninterrupted power to overall sa...

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

Prenatal to postnatal trajectory of brain growth in complex congenital heart disease

Altered brain development is a common feature of the neurological sequelae of complex congenital heart disease (CHD). These alterations include abnormalities in brain size and growth that begin prenatally and persist postnatally. However, t...

Characterization data on the topical carrier DDC642

This article contains original data, figures and methods used in the characterization of the liposomal carrier ‘DDC642’ for topical applications, described in “An elastic liposomal formulation for RNAi-based topical treatment of skin disord...

Ggtree: A serialized data object for visualization of a phylogenetic tree and annotation data

Abstract While phylogenetic trees and associated data have been getting easier to generate, it has been difficult to reuse, combine, and synthesize the information they provided, because published trees are often only available as image fil...

ANAT 2.0: reconstructing functional protein subnetworks

Abstract Background ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a number of ...

On Medical Informatics

This paper summarizes the author's point of view of defining medical informatics, to stimulate further discussions on how this "newly emerging discipline" should further proceed. We realize that the term "informatics" is related rather to t...

Where's the Science in Medical Informatics?

Charles P. Friedman, PhD; Where's the Science in Medical Informatics?, Journal of the American Medical Informatics Association, Volume 2, Issue 1, 1 January 199...

Medical Informatics and the Science of Cognition

Recent developments in medical informatics research have afforded possibilities for great advances in health care delivery. These exciting opportunities also present formidable challenges to the implementation and integration of technologie...

Recommendations of the International Medical Informatics Association (IMIA) on Education in Health and Medical Informatics

The International Medical Informatics Association (IMIA) agreed on international recommendations in health informatics/medical informatics education. These should help to establish courses, course tracks or even complete programs in this fi...

Patient-reported outcomes and measures for vaginal relaxation syndrome management: a systematic review

Abstract Background The heterogeneity of patient-reported outcomes (PROs) and patient-reported outcome measures (PROMs) in published clinical studies on vaginal relaxation syndrome (VRS) hinders cross-study comparisons and integration of ev...