Academic Articles & Research Papers

The Colorectal Cancer Screening Programme in the Basque Country: obtaining a good performance by means of professional collaboration

Introduction: The Basque Health Service approved the Colorectal Cancer (CRC) screening programme in 2008; targeted at residents (50 to 69 years old) estimated 598,201 by biennial faecal immunochemical test (FIT) and colonoscopy in positive ...

Health technology assessment

Health technology assessment (HTA) involves the systematic evaluation of healthcare technologies and the dissemination of assessment findings. Its main purpose is to provide objective information to support healthcare decisions and policy-m...

Effect of Interactive eHealth Interventions on Improving Medication Adherence in Adults With Long-Term Medication: Systematic Review

BackgroundMedication nonadherence leads to suboptimal treatment outcomes, making it a major priority in health care. eHealth provides an opportunity to offer medication adherence interventions with minimal effort from health care providers ...

Demonstration of high value care to improve oral health of a remote Indigenous community in Australia

Abstract Background The oral health of Indigenous children in remote communities is much worse than other population groups in Australia. Providing and maintaining an oral health service is challenging due to the remoteness of communities, ...

G-Aligner: a graph-based feature alignment method for untargeted LC–MS-based metabolomics

Abstract Background Liquid chromatography–mass spectrometry is widely used in untargeted metabolomics for composition profiling. In multi-run analysis scenarios, features of each run are aligned into consensus features by feature alignment ...

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adole...

The effect of structured medication review followed by face-to-face feedback to prescribers on adverse drug events recognition and prevention in older inpatients – a multicenter interrupted time series study

Abstract Background The effectiveness of interventions to improve medication safety in older inpatients is unclear, given a paucity of properly designed intervention studies applying clinically relevant endpoints such as hospital-acquired p...

Classroom Management Strategies of Multigrade Schools with Emphasis on the Role of Technology

Introduction : It appears that the effectiveness of a multigrade school class is dependent on the type of class management. Therefore this study aims to determine the classroom management strategies in multigrade schools with emphasis on th...

Effectiveness and Related Factors of Narrative Messages in Correcting Health-Related Misinformation: Protocol for a Systematic Review

BackgroundThe internet and social media have become essential sources of health information for patients and citizens; however, they often disseminate misinformation that lacks scientific evidence. Health-related misinformation can undermin...

An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement

This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving exist...

Impact of a Mobile App (LoAD Calc) on the Calculation of Maximum Safe Doses of Local Anesthetics: Protocol for a Randomized Controlled Trial

BackgroundLocal anesthetics (LAs) are regularly used to alleviate pain during medical or surgical procedures. Their use is generally considered safe, but exceeding the maximum recommended doses can lead to LA systemic toxicity, a rare but p...

A Focus on Simulation in Medical Informatics

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis

Objective: To summarize the key intervention characteristics and evaluate the effectiveness and safety of digital therapeutics (DTx) in patients receiving oral anticoagulation, with effectiveness evaluated using time in therapeutic range (T...

Adherence to Blended or Face-to-Face Smoking Cessation Treatment and Predictors of Adherence: Randomized Controlled Trial

BackgroundBlended face-to-face and web-based treatment is a promising way to deliver smoking cessation treatment. Since adherence has been shown to be an indicator of treatment acceptability and a determinant for effectiveness, we explored ...

Toward Home‐Based Telerehabilitation for Cerebral Palsy Patients: A Qualitative Study on Feasibility, Barriers and Facilitators

ABSTRACT Background and Aim Telerehabilitation has emerged as a promising solution to address accessibility, cost‐effectiveness, and continuity of care for patients requiring long‐term rehabilitation, like cerebral palsy (CP) patients. This...

e-Health interventions for healthy aging: a systematic review

Abstract Background Healthy aging (HA) is a contemporary challenge for population health worldwide. Electronic health (e-Health) interventions have the potential to support empowerment and education of adults aged 50 and over. Objectives To...

Effectiveness of Social Cognitive Theory–Based Interventions for Glycemic Control in Adults With Type 2 Diabetes Mellitus: Protocol for a Systematic Review and Meta-Analysis

BackgroundFor those living with type 2 diabetes mellitus (T2DM), failing to engage in self-management behaviors leads to poor glycemic control. Social cognitive theory (SCT) has been shown to improve health behaviors by altering cognitive p...

Comparative Effectiveness Research and Medical Informatics

A Collaborative Approach to Improving Breast Cancer Screening and Follow-Up Through Multicomponent Interventions and Process Improvements: The Links to Care Community Grants Project study protocol and baseline findings

Background: The Links to Care Community Grants Project was developed to improve breast cancer outcomes by increasing access to appropriate follow-up care, improving processes for care transitions, and enhancing care coordination between com...

Characterization data on the topical carrier DDC642

This article contains original data, figures and methods used in the characterization of the liposomal carrier ‘DDC642’ for topical applications, described in “An elastic liposomal formulation for RNAi-based topical treatment of skin disord...