Academic Articles & Research Papers

S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets

Base on the sequence of S genes, which encode spike proteins, we previously identified three different types (North American, S INDEL, and S large-DEL types) of porcine epidemic diarrhea virus (PEDV) that have re-emerged in Japan since 2013...

Glycosylation of Epigallocatechin Gallate by Engineered Glycoside Hydrolases from <i>Talaromyces amestolkiae</i>: Potential Antiproliferative and Neuroprotective Effect of These Molecules

Glycoside hydrolases (GHs) are enzymes that hydrolyze glycosidic bonds, but some of them can also catalyze the synthesis of glycosides by transglycosylation. However, the yields of this reaction are generally low since the glycosides formed...

The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism underlying the ULK complex assembly have yet to be ...

Beginning at the ends: telomeres and human disease [version 1; referees: 4 approved]

Studies of rare and common illnesses have led to remarkable progress in the understanding of the role of telomeres (nucleoprotein complexes at chromosome ends essential for chromosomal integrity) in human disease. Telomere biology disorders...

P415: TARGETED 3RD-GENERATION (NANOPORE) SEQUENCING REVEALS MANY NOVEL CIRCULAR RNAS OF THE APOPTOSIS-RELATED BCL2L12 GENE, EXPRESSED IN HUMAN CELLS FROM ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROMES

Molecular biology and biochemistry of the endothelins

Molecular Biology and Biotechnology

One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular text...

Molecular Biology of the Gene

The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA doub...

Metal-Ligand Coordination Nanomaterials Tailored to the Cancer-Immunity Cycle.

Innovative green niosomal piperlongumine as a novel topical treatment for dermatophytosis in guinea pigs model

Abstract Dermatophytosis is a common superficial fungal infection that affects many people worldwide. Although various species of dermatophytes respond to common antifungal drugs, the recently identified Trichophyton indotineae isolates hav...

Targeting Inflammation With Nanosized Drug Delivery Platforms in Cardiovascular Diseases: Immune Cell Modulation in Atherosclerosis

Atherosclerosis (AS) is a disorder of large and medium-sized arteries; it consists in the formation of lipid-rich plaques in the intima and inner media, whose pathophysiology is mostly driven by inflammation. Currently available interventio...

Graphene Quantum Dots Modified with Metformin/Co(II) as Efficient Oxidation Catalyst

While one of the valuable approaches to obtaining a heterogeneous catalyst is supporting them on a high surface area supports, the strategy mainly suffers from the low number of chelating agents on most of the supports to grip the metal cat...

The miRNA neuroinflammatory biomarkers in COVID-19 patients with different severity of illness

Introduction: The expression of specific miRNAs and their mRNA targets are changed in infectious disease. The aim of this study was to analyze the expression of pro-neuroinflammatory miRNAs, anti-neuroinflammatory miRNAs, and their mRNA tar...

A Competitive Design and Material Consideration for Fabrication of Polymer Electrolyte Membrane Fuel Cell Bipolar Plates

The bipolar plate is one of the most significant components of a polymer electrolyte membrane (PEM) fuel cell, and contributes substantially to the cost structure and the weight of the stacks. A number of graphite polymer composites with di...

Externally triggered drug delivery systems

Externally triggered drug delivery systems empower patients or healthcare providers to utilize external stimuli to initiate drug release from implanted systems. This approach holds significant potential for clinical disease management, offe...

Nitrogen-Doped Mesoporous Carbon Microspheres by Spray Drying-Vapor Deposition for High-Performance Supercapacitor

Nitrogen-doped mesoporous carbon microspheres have been successfully synthesized via a spray drying-vapor deposition method for the first time, using commercial Ludox silica nanoparticles as hard templates. Compared to freeze-drying and air...

Physics, chemistry and biology of functional nanostructures II

Dendritic boron and nitrogen doped high-entropy alloy porous carbon fibers for high-efficiency hydrogen evolution reaction

Summary: Among various electrocatalysts, high-entropy alloys (HEAs) have gained significant attention for their unique properties and excellent catalytic activity in the hydrogen evolution reaction (HER). However, the precise synthesis of H...

Enhancing the oxidative cleavage of vicinal diols on Fe-ZSM-5 catalysts with hierarchical porosity

The oxidative cleavage of biomass-derived vicinal diols holds significant potential for producing valuable renewable carboxylic acids. Fe-ZSM-5 zeolite is a highly effective catalyst for this reaction using mild reaction conditions; however...

Nanotechnology: A Revolution in Modern Industry

Nanotechnology, contrary to its name, has massively revolutionized industries around the world. This paper predominantly deals with data regarding the applications of nanotechnology in the modernization of several industries. A comprehensiv...