Academic Articles & Research Papers

Using deep learning to predict tyrosinase inhibitors for treating hyperpigmentation disorders

Background In recent years, skin health has garnered widespread attention, with hyperpigmentation disorders caused by excessive melanin deposition emerging as a particularly prominent concern. Tyrosinase, as the rate-limiting enzyme in the ...

Deep learning for computational chemistry

The rise and fall of artificial neural networks is well documented in the scientific literature of both computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning,...

A Cardiovascular Disease Prediction Model Based on Routine Physical Examination Indicators Using Machine Learning Methods: A Cohort Study

BackgroundCardiovascular diseases (CVD) are currently the leading cause of premature death worldwide. Model-based early detection of high-risk populations for CVD is the key to CVD prevention. Thus, this research aimed to use machine learni...

Machine learning for advanced energy materials

The screening of advanced materials coupled with the modeling of their quantitative structural-activity relationships has recently become one of the hot and trending topics in energy materials due to the diverse challenges, including low su...

A cascaded classification approach using transfer learning and feature engineering for improved breast cancer classification

The primary objective of this study is to design a cascaded classification framework that integrates deep-learning representations with handcrafted and clinical features to enhance the reliability and accuracy of breast cancer detection in ...

Passive early screening for Alzheimer's disease and related dementias using EHR comorbidity patterns.

Identification of novel serotonin transporter (SERT) inhibitors via large-scale machine learning-based virtual screening and molecular dynamics simulations.

High temperature Nb-Si alloys using data science: optimization of fracture toughness and high-temperature strength

Abstract High temperature Nb-Si based alloys face a critical challenge: achieving adequate room-temperature fracture toughness ( > 18 MPa·m1/2) for processing while maintaining high-temperature strength, properties that typically compete wi...

Machine Learning in Virtual Screening

In this review, we highlight recent applications of machine learning to virtual screening, focusing on the use of supervised techniques to train statistical learning algorithms to prioritize databases of molecules as active against a partic...

Applying the Information-Motivation-Behavioral Skills Model to a Virtual Reality-Assisted Cognitive Health Education Intervention to Promote Screening Uptake: Qualitative Study.

From multi-omics screening to functional validation: The SOD1-SIRT5 Axis as a potential mediator of ammonia-related neuronal injury and NAD⁺-based neuroprotection in epilepsy.

PosturAll: A Posture Assessment Software for Children

From an early age, people are exposed to risk factors that can lead to musculoskeletal disorders like low back pain, neck pain and scoliosis. Medical screenings at an early age might minimize their incidence. The study intends to improve a ...

Directed Evolution of Near-Infrared Serotonin Nanosensors with Machine Learning-Based Screening

In this study, we employed a novel approach to improve the serotonin-responsive ssDNA-wrapped single-walled carbon nanotube (ssDNA-SWCNT) nanosensors, combining directed evolution and machine learning-based prediction. Our iterative optimiz...

The Role of Artificial Intelligence in Early Cancer Diagnosis

Improving the proportion of patients diagnosed with early-stage cancer is a key priority of the World Health Organisation. In many tumour groups, screening programmes have led to improvements in survival, but patient selection and risk stra...

Economic Evaluations of Artificial Intelligence Implementation in Diabetic Retinopathy Screening

Diabetic retinopathy (DR) is a common complication of diabetes that damages retinal blood vessels and can lead to vision impairment. The application of Artificial Intelligence (AI) in DR screening offers a promising alternative to conventio...

Artificial intelligence in pancreatic cancer

Pancreatic cancer is the deadliest disease, with a five-year overall survival rate of just 11%. The pancreatic cancer patients diagnosed with early screening have a median overall survival of nearly ten years, compared with 1.5 years for th...

Spatio-temporal assessment of Toumeyella parvicornis spread in mediterranean coastal pine forests through sentinel-2 data

Mediterranean coastal pine forests offer vital ecological and cultural benefits but face threats from climate change, urbanization, and pests. Among invasive agents, Toumeyella parvicornis is a severe threat to Pinus pinea along Italy's coa...

Cervical Cancer Diagnosis Based on Multi-Domain Features Using Deep Learning Enhanced by Handcrafted Descriptors

Cervical cancer, among the most frequent adverse cancers in women, could be avoided through routine checks. The Pap smear check is a widespread screening methodology for the timely identification of cervical cancer, but it is susceptible to...

A machine learning approach predicts future risk to suicidal ideation from social media data

Abstract Machine learning analysis of social media data represents a promising way to capture longitudinal environmental influences contributing to individual risk for suicidal thoughts and behaviors. Our objective was to generate an algori...

Women’s perceptions and attitudes towards the use of AI in mammography in Sweden: a qualitative interview study

Background Understanding women’s perspectives can help to create an effective and acceptable artificial intelligence (AI) implementation for triaging mammograms, ensuring a high proportion of screening-detected cancer. This study aimed to e...