Reset
Showing 20 of 7,048 academic articles

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

A sustainable supramolecular deep eutectic solvent system for dispersive liquid–liquid microextraction followed by HPLC for the determination of melamine in milk samples

Modar Sadek, Nazira Sarkis, George Jangi • Results in Chemistry (2026)

This work presents the development and application of an innovative green supramolecular deep eutectic solvent (SUPRADES)-based DLLME approach for the extraction and quantification of melamine in milk matrices. For this purpose, thymol and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2026.103057

Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Christian G. Ziegler, Carina Riediger, Matthias Gruber, Carola Kunath et al. • Frontiers in Endocrinology (2022)

Pheochromocytomas (PCCs) are rare but potentially lethal tumors that arise from the adrenal medulla. The clinical suspicion and diagnosis of PCC can be challenging due to the non-specific nature of signs and symptoms. In many patients, infe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2022.967995

Impact of Ultra-High Pressure Homogenization on the Structural Properties of Egg Yolk Granule

Romuald Gaillard, Alice Marciniak, Guillaume Brisson, Véronique Perreault et al. • Foods (2022)

Ultra-high pressure homogenization (UHPH) is a promising method for destabilizing and potentially improving the techno-functionality of the egg yolk granule. This study’s objectives were to determine the impact of pressure level (50, 175 an...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods11040512

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

Diletta Fontana, Mario Mauri, Rossella Renso, Mattia Docci et al. • Nature Communications (2020)

ETNK1 mutations are recurrent in leukemia but how they contribute to oncogenesis is still unclear. Here, the authors show that ETNK1 mutations increase mitochondrial activity, ROS and H2AX levels and that these effects can be rescued upon p...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-020-19721-w

Development and Comprehensive Diverse-Matrix Evaluation of Four PAHs Using Solvent-Modified QuEChERS-GC-MS with Freeze-Out

Kyung-Jik Lim, Hyun-Jun Kim, Yu-Jin Heo, Han-Seung Shin • Foods (2025)

Polycyclic aromatic hydrocarbons (PAHs) are recognized carcinogens that enter the food chain through pre-existing environmental contamination (air, water, soil), and their formation and accumulation during food preparation and processing in...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods14172979

Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

Karin Jonsson, My Green, Malin Barman, Agneta Sjöberg et al. • Food & Nutrition Research (2016)

Background: A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and ...

DOAJ Open Access (DOAJ) DOI: 10.3402/fnr.v60.32721

Chemical Diversity of Fuzhuan Brick Teas from Hunan and Shaanxi

ZHANG Ning, YU Shilan, YAN Haoyi, ZHANG Yunjun, HAN Xiaoyu, REN Hongyu, CHEN Yuqing, LING Tiejun, AN Maoqiang • Shipin Kexue (2024)

This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick tea and ...

DOAJ Open Access (DOAJ) DOI: 10.7506/spkx1002-6630-20231108-066

Alleviation effect of glycyrrhetinic acid on zearalenone-induced reproductive toxicity in replacement gilts

Li-Tao Che, Li-Tao Che, Ahmed H. El-Sappah, Ahmed H. El-Sappah et al. • Frontiers in Veterinary Science (2025)

IntroductionThis study investigated whether glycyrrhetinic acid (GA) can alleviate the reproductive toxicity of Zearalenone (ZEN) in replacement gilts.MethodsEighty Landrace × Yorkshire gilts were randomly assigned to four dietary groups: c...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2025.1636738

Unraveling the formation mechanism of 3-methylindole from tryptophan in the glucose-mediated Maillard reaction: a combined ReaxFF MD, DFT, and experimental study

Yuan-Yuan Yang, Chao-Kun Wei, Xin Pan, An-Ran Zheng et al. • Food Chemistry: X (2026)

3-Methylindole is a concentration-dependent aroma compound, and its formation mechanism in the tryptophan-glucose Maillard reaction is crucial for flavor regulation but remains incompletely elucidated. Using gas chromatography-olfactometry-...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fochx.2026.104719

Biophysical and textural attributes as selection indices for replacing the adopted cassava variety with the improved genotype to produce fufu

Wasiu Awoyale, Wasiu Awoyale, Busie Maziya-Dixon, Hakeem Oyedele et al. • Frontiers in Sustainable Food Systems (2023)

The use of the biophysical and textural qualities of fufu to choose the possible substitution of an adopted cassava variety (TMEB419-V1) with improved genotypes from the breeding program was assessed in this study. Standard methods were use...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2023.1272724

Optimization of lactic fermentation parameters of sugar beet (Beta vulgaris L.) puree with Lactobacillus plantarum and Lactobacillus casei

S. Khalajian, N. Mooraki, M. Honarvar, A. Akhavan Sepahi • Applied Food Research (2026)

This research investigates the lactic fermentation process of sugar beet (Beta vulgaris L.) puree with the aim of creating a functional probiotic product. The focus is on optimizing fermentation conditions to enhance health benefits, thereb...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.afres.2026.101754

Emodin, an Emerging Mycotoxin, Induces Endoplasmic Reticulum Stress-Related Hepatotoxicity through IRE1α–XBP1 Axis in HepG2 Cells

Su Been Park, Gun Hee Cho, Young Eun Park, Hyang Sook Chun • Toxins (2023)

Emodin, an emerging mycotoxin, is known to be hepatotoxic, but its mechanism remains unclear. We hypothesized that emodin could induce endoplasmic reticulum (ER) stress through the inositol-requiring enzyme 1 alpha (IRE1α)–X-box-binding pro...

DOAJ Open Access (DOAJ) DOI: 10.3390/toxins15070455

Exploring Volatile Profiles and De-Flavoring Strategies for Enhanced Acceptance of Lentil-Based Foods: A Review

Francesca Vurro, Davide De Angelis, Giacomo Squeo, Francesco Caponio et al. • Foods (2024)

Lentils are marketed as dry seeds, fresh sprouts, flours, protein isolates, and concentrates used as ingredients in many traditional and innovative food products, including dairy and meat analogs. Appreciated for their nutritional and healt...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods13162608

Effects of Hot Air-drying and Vacuum Freeze-drying on Flavor Components in Different Parts of Hericium erinaceus

Yihang ZHANG, Donglu FANG, Lei ZHONG, Qiuhui HU et al. • Shipin gongye ke-ji (2022)

In order to explore the changes of flavor characteristics of Hericium erinaceus before and after drying, the effects of hot air-drying and vacuum freeze-drying on flavor components of pileus and stipe of H. erinaceus were studied using high...

DOAJ Open Access (DOAJ) DOI: 10.13386/j.issn1002-0306.2021070247

Natural Polyphenols for the Preservation of Meat and Dairy Products

Hammad Ullah, Yaseen Hussain, Cristina Santarcangelo, Alessandra Baldi et al. • Molecules (2022)

Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, sa...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27061906