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Identification of Specific IgE Antibodies and Asthma Control Interaction and Association Using Cluster Analysis in a Bulgarian Asthmatic Children Cohort

Snezhina Lazova, Tsvetelina Velikova, Stamatios Priftis, Guergana Petrova • Antibodies (2020)

(1) Background: Asthma is a complex heterogeneous disease that likely comprises several distinct disease phenotypes, where the clustering approach has been used to classify the heterogeneous asthma population into distinct phenotypes; (2) M...

DOAJ Open Access (DOAJ) DOI: 10.3390/antib9030031

Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Kapil Sayal, Laura Wyatt, Louise Thomson, Grace Holt et al. • Health Technology Assessment (2025)

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

DOAJ Open Access (DOAJ) DOI: 10.3310/GJKS0519

Recent advances in benzo[a]phenoxazine-based fluorescent probes: a review and perspectives

Kalayou Hiluf Gebremdhin, Mebrahtom Gebrelibanos Hiben, Hagos Feleke Gebremariam, Hagos Hailu Kassegn et al. • Journal of Photochemistry and Photobiology (2026)

Benzo[a]phenoxazine (BPO) based molecules have been recently emerged as a new class of near-infrared (NIR) fluorophore for image-guided diagnosis in cancer research. The successful application of BPOs as NIR fluorophore in biomedical resear...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpap.2026.100280

Detection of causative agents of bacterial pneumonia in hospitalized hajj and umrah cases by multiplex real-time polymerase chain reaction

Vivi Setiawaty, Dini Darmawati, Arie Ardiansyah Nugraha, Pancrasia Maria Hendrati • Iranian Journal of Microbiology (2022)

Background and Objectives: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is commonly detected in pneumonia patients who travel from the Middle East regions. Besides MERS-CoV, many other pathogenic agents cause pneumonia. Detection...

DOAJ Open Access (DOAJ)

The Colorectal Cancer Screening Programme in the Basque Country: obtaining a good performance by means of professional collaboration

Isabel Portillo, Isabel Idigoras, Isabel Bilbao, Jose Luis Hurtado et al. • International Journal of Integrated Care (2019)

Introduction: The Basque Health Service approved the Colorectal Cancer (CRC) screening programme in 2008; targeted at residents (50 to 69 years old) estimated 598,201 by biennial faecal immunochemical test (FIT) and colonoscopy in positive ...

DOAJ Open Access (DOAJ) DOI: 10.5334/ijic.s3166

Formative qualitative research on the potential for digital solutions to address diabetes care gaps in Tanzania and Sri Lanka

Ishu Kataria, Kaushik Ramaiya, Omary Ubuguyu, Sumithra Krishnamurthy Reddiar et al. • BMJ Open (2024)

Objectives Diabetes care remains unavailable and unaffordable for many people. Adapting models of care to low-income and middle-income country contexts is a priority. Digital technology offers substantial potential yet must surmount health ...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-078845

Medical Informatics and Preparedness

Patrícia Flatley Brennan • Journal of the American Medical Informatics Association (2002)

The terrorist attacks of September 2001 and the subsequent deliberate dissemination of anthrax have stimulated public awareness of the need in both the public health and clinical health care systems to quickly detect and respond to altered ...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1060 PMC: 344577

Real-World Evaluation of AI-Driven Diabetic Retinopathy Screening in Public Health Settings: Validation and Implementation Study

Mona Duggal, Anshul Chauhan, Vishali Gupta, Ankita Kankaria et al. • JMIR Medical Informatics (2025)

Abstract BackgroundArtificial intelligence (AI) algorithms offer an effective solution to alleviate the burden of diabetic retinopathy (DR) screening in public health settings. However, there are challenges in translating diagno...

DOAJ Open Access (DOAJ) DOI: 10.2196/67529

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Mário João Fartaria, Tobias Kober, Cristina Granziera, Meritxell Bach Cuadra • NeuroImage: Clinical (2019)

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-co...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2019.101938

A method for automatically extracting infectious disease-related primers and probes from the literature

Pérez-Rey David, de la Iglesia Diana, de la Calle Guillermo, López-Campos Guillermo et al. • BMC Bioinformatics (2010)

Abstract Background Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the diagnosis and prescription of infectious diseases. Th...

DOAJ Open Access (DOAJ) DOI: 10.1186/1471-2105-11-410

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Vera Russmann, Matthias Brendel, Erik Mille, Angela Helm-Vicidomini et al. • NeuroImage: Clinical (2017)

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2017.04.003

Functional neuroimaging of visuospatial working memory tasks enables accurate detection of attention deficit and hyperactivity disorder

Rubi Hammer, Gillian E. Cooke, Mark A. Stein, James R. Booth • NeuroImage: Clinical (2015)

Finding neurobiological markers for neurodevelopmental disorders, such as attention deficit and hyperactivity disorder (ADHD), is a major objective of clinicians and neuroscientists. We examined if functional Magnetic Resonance Imaging (fMR...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2015.08.015

A novel and accelerated method for integrated alignment and variant calling from short and long reads

Jinnan Hu, Donald Freed, Hanying Feng, Hong Chen et al. • Frontiers in Bioinformatics (2026)

BackgroundIntegrating short- and long-read sequencing technologies has become a promising approach for achieving accurate and comprehensive genomic analysis. Although short-read sequencing (Illumina, etc.) offers high base accuracy and cost...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbinf.2025.1691056

Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial

D. Ontaneda, P. Sati, P. Raza, M. Kilbane et al. • NeuroImage: Clinical (2021)

The specificity and implementation of current MRI-based diagnostic criteria for multiple sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are eventually determined not to have the disease, with overrelianc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102834

Multi-label classification of fundus images based on graph convolutional network

Yinlin Cheng, Mengnan Ma, Xingyu Li, Yi Zhou • BMC Medical Informatics and Decision Making (2021)

Abstract Background Diabetic Retinopathy (DR) is the most common and serious microvascular complication in the diabetic population. Using computer-aided diagnosis from the fundus images has become a method of detecting retinal diseases, but...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12911-021-01424-x

Fusing content and social relationships: a multi-modal heterogeneous graph transformer approach for social bot detection

Jianhong Luo, Chaoqi Jin • EPJ Data Science (2025)

Abstract Social bots pose a significant threat to online platforms, demanding robust methods to detect their increasingly complex behaviors. This paper introduces MM-HGT-Bot, a multi-modal framework that advances the field by operationalizi...

DOAJ Open Access (DOAJ) DOI: 10.1140/epjds/s13688-025-00583-5

Grey matter volume associations with personality functioning in a clinical cohort of female youths

Madelyn Thomson, Marialuisa Cavelti, Ines Mürner-Lavanchy, Silvano Sele et al. • NeuroImage: Clinical (2026)

Borderline Personality Disorder (BPD) is a severe mental illness, although its neurobiological underpinnings remain largely unknown. Structural Magnetic Resonance Imaging (sMRI) in adolescents can offer insights into potential biomarkers to...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2026.103988