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Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Yu -Yang Ma, Hai-Yan Li, Ruo-Nan Yao, Gong Cheng et al. • Experimental Gerontology (2025)

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112946

Effective analysis of neurotoxicity and mechanisms of dioctyl terephthalate using network toxicology

Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience (2026)

ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2026.1783807

Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA)

Reagan E. Garcia, Anne B. Newman, Eileen Johnson, Yujia Susanna Qiao et al. • Sensors (2025)

Fatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associated with fa...

DOAJ Open Access (DOAJ) DOI: 10.3390/s25092722

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus (2025)

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100171

Nutritional status, literacy, and risk factors of malnutrition in the population over 50 years of age - findings from the SHARE project

Tereza Vágnerová, Olga Dvořáčková, Eva Topinková • Clinical Nutrition Open Science (2024)

Summary: Background & Aims: The transition from middle age to old age (from adults aged 50–55 years to older seniors aged 75–80 years) represents a critical period in terms of changes in body composition, i.e., increase in body fat per...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nutos.2024.01.006

Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits

Mateus H. Gouveia, Amy R. Bentley, Hampton Leonard, Karlijn A. C. Meeks et al. • Scientific Reports (2021)

Abstract Genome-wide association studies (GWAS) have identified thousands of genetic loci associated with cross-sectional blood pressure (BP) traits; however, GWAS based on longitudinal BP have been underexplored. We performed ethnic-specif...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-83450-3

Diffuse hypertrophic obstructive cardiomyopathy complicated by apical ventricular aneurysm and excessive left ventricular trabeculation: a case report

Ying Li, Ying Li, Na Jia, Xinyue Li et al. • Frontiers in Cardiovascular Medicine (2026)

This article reports a rare case of diffuse hypertrophic obstructive cardiomyopathy complicated with left ventricular apical aneurysm and excessive trabeculation. Genetic testing of the patient revealed a heterozygous variant of the MYBPC3 ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2026.1753832

Associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older adults

Emi Miki, Risa Kawabata • Cadernos Brasileiros de Terapia Ocupacional (2020)

This study aimed to investigate the associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older Japanese adults by examining the correlations between the Canadian Occup...

DOAJ Open Access (DOAJ) DOI: 10.4322/2526-8910.ctoAO2096

HEART Camp Connect—Promoting adherence to exercise in adults with heart failure with preserved ejection fraction

Windy W. Alonso, Sara E. Bills, Scott W. Lundgren, Steven J. Keteyian et al. • ESC Heart Failure (2025)

Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF)....

DOAJ Open Access (DOAJ) DOI: 10.1002/ehf2.15341

Decreased Daily Melatonin Levels in Women with Systemic Lupus Erythematosus - A Short Report

Ralitsa Robeva, Georgi Kirilov, Dobromir Tanev, Analia Tomova et al. • Balkan Medical Journal (2013)

Background: The neuroendocrine system is known to influence immunity, but the precise interactions between different hormones and autoimmune disorders remain obscure. Aims: The present study aimed to investigate the role of daily serum ...

DOAJ Open Access (DOAJ) DOI: 10.5152/balkanmedj.2013.8064

Having More Daughters Independently Predicts Home Discharge in Stroke Patients Admitted to Inpatient Rehabilitation Ward

Shiau-Fu Hsieh, Kuo-Liong Chien, Chu-Hao Weng, Yi-Ping Chiang • International Journal of Gerontology (2017)

Background: The predictors for failure of home discharge after post-acute inpatient stroke rehabilitation need investigation. Methods: With this retrospective case-control study conducted in a stroke rehabilitation unit in one tertiary hosp...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijge.2017.07.005

A review of studies that used B mode ultrasound to estimate age-related changes in anterior thigh skeletal muscle thickness across the adult lifespan

Isobel Jacob, Gareth Jones, Peter Francis, Mark I Johnson • Archives of Gerontology and Geriatrics Plus (2024)

Background: The purpose of this review was to synthesise and determine the age-related change per annum in muscle thickness of the anterior thigh across the adult lifespan. Methods: Electronic databases (PubMed, SPORTDiscus and MEDLINE) wer...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2024.100037

Music therapy-induced changes in salivary cortisol level are predictive of cardiovascular mortality in patients under maintenance hemodialysis

Hou YC, Lin YJ, Lu KC, Chiang HS et al. • Therapeutics and Clinical Risk Management (2017)

Yi-Chou Hou,1 Yen-Ju Lin,2 Kuo-Cheng Lu,1 Han-Sun Chiang,3 Chia-Chi Chang,4 Li-King Yang1 1Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, 2Department of Nursing, Taipei Medical Univ...

DOAJ Open Access (DOAJ)

Residential Satisfaction of Rural Older Adults Aging in Place

Sung-Jin Lee PhD, Kathleen Rose Parrott PhD, Minyong Lee PhD, Sheryl Renee Robinson BS et al. • Gerontology and Geriatric Medicine (2021)

This study explored residential (housing and town) satisfaction of rural older adults aging in place, relating to demographic and housing characteristics. We conducted a structured, face-to-face survey with 149 rural older adults. Regressio...

DOAJ Open Access (DOAJ) DOI: 10.1177/2333721421997190

Extreme heat in India and anthropogenic climate change

G. J. van Oldenborgh, S. Philip, S. Kew, M. van Weele et al. • Natural Hazards and Earth System Sciences (2018)

On 19 May 2016 the afternoon temperature reached 51.0 °C in Phalodi in the northwest of India – a new record for the highest observed maximum temperature in India. The previous year, a widely reported very lethal heat wave occurred...

DOAJ Open Access (DOAJ) DOI: 10.5194/nhess-18-365-2018

Sources of Contaminants of Emerging Concern in Groundwater of Barcelona Urban Area

D. Schmidlin, L. Scheiber, M. Teixidó, E. Vázquez et al. • Advances in Geosciences (2023)

Groundwater is a vital resource for the development of urban areas, where the problem focuses on the quantity and on the quality of this freshwater resource. Barcelona is a good example as because currently groundwater is used for irrigatio...

DOAJ Open Access (DOAJ) DOI: 10.5194/adgeo-59-59-2023

Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia

Masanobu Kogure, Nobuhisa Kanahara, Atsuhiro Miyazawa, Atsuhiro Miyazawa et al. • Frontiers in Psychiatry (2024)

BackgroundMost genetic analyses that have attempted to identify a locus or loci that can distinguish patients with treatment-resistant schizophrenia (TRS) from those who respond to treatment (non-TRS) have failed. However, evidence from mul...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2023.1334335

High-quality read-based phasing of cystic fibrosis cohort informs genetic understanding of disease modification

Scott Mastromatteo, Angela Chen, Jiafen Gong, Fan Lin et al. • HGG Advances (2023)

Summary: Phasing of heterozygous alleles is critical for interpretation of cis-effects of disease-relevant variation. We sequenced 477 individuals with cystic fibrosis (CF) using linked-read sequencing, which display an average phase block ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.xhgg.2022.100156