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Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition.
Wu D, Zhu C, Pan H, Xu H, Xu J, Liu Y, Wang S, Xiao M, Yu X, Shi S

Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition.

Medicine & Health Published 2026 Verification Pending

Overview & Synopsis

Open access biomedical research article published in Gut.

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Indexed from repository: PubMed Central (pmc.ncbi.nlm.nih.gov)
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Document Information

Document Title Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition.
Author / Organization Wu D, Zhu C, Pan H, Xu H, Xu J, Liu Y, Wang S, Xiao M, Yu X, Shi S
Subject & Discipline Gut
Categories Medicine & Health
Publication Year 2026
License / Rights Open Access / Creative Commons
Resource Verification Listed PDF (Verification Pending)
Original Host Website PubMed Central (pmc.ncbi.nlm.nih.gov)
File Format application/pdf (Portable Document Format)
Language EN
Catalog ID DOC-46373
Original Source Link Visit Source Page on pmc.ncbi.nlm.nih.gov »