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Reversible, Orally Bioavailable Small-Molecule Inhibitors Occupy the Substrate Tunnel of the Thioesterase Domain of Fatty Acid Synthase.
Fromm J, Aleshin A, Lambert LJ, De Backer LJS, Ganji SR, Mattmann ME, Limpert AS, Gosalia P, Wimer CD, Layng FI, Celeridad M, Ardecky R, Teriete P, Scott DA, Hedrick MP, Smith JW, Sheffler DJ, Cosford NDP

Reversible, Orally Bioavailable Small-Molecule Inhibitors Occupy the Substrate Tunnel of the Thioesterase Domain of Fatty Acid Synthase.

Medicine & Health Published 2026 Verification Pending

Overview & Synopsis

Open access biomedical research article published in bioRxiv.

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Indexed from repository: PubMed Central (pmc.ncbi.nlm.nih.gov)
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Document Title Reversible, Orally Bioavailable Small-Molecule Inhibitors Occupy the Substrate Tunnel of the Thioesterase Domain of Fatty Acid Synthase.
Author / Organization Fromm J, Aleshin A, Lambert LJ, De Backer LJS, Ganji SR, Mattmann ME, Limpert AS, Gosalia P, Wimer CD, Layng FI, Celeridad M, Ardecky R, Teriete P, Scott DA, Hedrick MP, Smith JW, Sheffler DJ, Cosford NDP
Subject & Discipline bioRxiv
Categories Medicine & Health
Publication Year 2026
License / Rights Open Access / Creative Commons
Resource Verification Listed PDF (Verification Pending)
Original Host Website PubMed Central (pmc.ncbi.nlm.nih.gov)
File Format application/pdf (Portable Document Format)
Language EN
Catalog ID DOC-20465
Original Source Link Visit Source Page on pmc.ncbi.nlm.nih.gov »