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The development and function of the central nervous system rely on the microtubule (MT) and actin cytoskeletons and their respective effectors. Although the structural role of the cytoskeleton has long been acknowledged ...
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SUMMARY In neurons, dynamic microtubules play regulatory roles in neurotransmission and synaptic plasticity. While stable microtubules contain detyrosinated tubulin, dynamic microtubules are composed of tyrosinated tubul...
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The aims of this study were, analysing the effects of rearing managements, carcass traits, and muscle type (M. complexus [CP], M. infraspinatus [IF], M. longissimus [LM], M. rhomboideus [RH], and M. serratus ventralis [S...
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Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory interneurons marks the closure of critical periods of high plasticity, whereas PNN removal reinstates juvenile plasticity in the adult cor...
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L’objectif de cette thèse est d’évaluer, à travers une étude rétrospective menée sur une période de 20 ans, la prévalence et la distribution des lésions des muqueuses orales au sein d’un service de consultation spécialis...
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Objective Peripheral ulcerative keratitis (PUK) is a rare but severe ocular complication of rheumatoid arthritis (RA). It can be considered as an ocular manifestation of rheumatoid vasculitis (RV). Our case series aimed ...
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Chondrites are rocky fragments of asteroids that formed at different times and heliocentric distances in the early solar system. Most chondrite groups contain water-bearing minerals, attesting that both water-ice and dus...
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CRISPR-Cas9 is a promising technology for gene therapy. However, the ON-target genotoxicity of CRISPR-Cas9 nuclease due to DNA double-strand breaks has received little attention and is probably underestimated. Here we re...
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Driving automation, either level 3 (including unplanned manual control recovery) or level 4 (fully automated driving on specific road sections), introduces new safetyand acceptance issues. In order to improve road safety...
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Supported transition metal materials have been identified as ideal candidates for decades to catalyze various reactions of interest in the fields of hydrocarbon refining, energy and environmental catalysis. As the resour...
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Background: Recent studies report very low adherence of practitioners to ATS/IDSA recommendations for the treatment of nontuberculous mycobacteria pulmonary disease (NTM-PD), as well as a great variability of practices. ...
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This paper discusses the use of robust schedules for facing uncertainty arising in crossdock truck scheduling problems. Groups of permutable operations bring sequential flexibility in the schedule, allowing to deal with ...
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Instability and mixing are ubiquitous processes in river plumes but their small spatial and temporal scales often limit their observation and analysis. We investigate flow instability and mixing processes in the Gironde ...
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The production of dairy powders has significantly increased in the last decade and, currently,it represents a fundamental portion of the dairy industry market.Controlling and improving powder nutritional properties has b...
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The SorLA protein, encoded by the SORL1 gene, is a major player in Alzheimer's disease (AD) pathophysiology. Functional and genetic studies demonstrated that SorLA deficiency results in increased production of Aβ peptide...