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Abstract Synaptic activity results in long-lasting alterations of neuronal properties, which require gene expression regulation. PYK2 is a calcium-activated non-receptor protein tyrosine kinase highly expressed in hippoc...
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The main neuropathological hallmarks of Alzheimer’s disease (AD) are the extracellular senile plaques composed of amyloid-β peptide (Aβ) and the intracellular neurofibrillary tangles composed of hyperphosphorylated Tau. ...