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Song My Hoang, Nicole Kaminski, Ragini Bhargava, Jonathan Barroso-González, Michelle L Lynskey, Laura García-Expósito, Justin L Roncaioli, Anne R Wondisford, Callen T Wallace, Simon Watkins, Dominic I James, Ian D Waddell, Donald Ogilvie, Kate M Smith, Felipe da Veiga Leprevost, Dattatreya Mellacharevu, Alexey I Nesvizhskii, Jianfeng Li, Dominique Ray-Gallet, Robert W Sobol, Geneviève Almouzni, Roderick J O’sullivan
Found 1 document(s)
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Year: 2020 •
Source: hal.science •
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The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by poly(ADP-ribose) glycohydrolase (PARG) is essential for prog...