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We present measurements of black hole masses and Eddington ratios (ฮป Edd) for a sample of 38 bright (M 1450 < -24.4 mag) quasars at 5.8 โฒ z โฒ 7.5, derived from Very Large Telescope/X-shooter near-IR spectroscopy of their...
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The program-over-monoid model of computation originates with Barrington's proof that the model captures the complexity class $\mathsf{NC^1}$. Here we make progress in understanding the subtleties of the model. First, we ...
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We have explored the dynamical and mass evolution of halos driven by large-scale filaments using a dark-matter-only cosmological simulation with the help of a phase-space analysis. Since a nonnegligible number of galaxie...
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The quantification of the effects of surface waves on the seismic vulnerability of structures becomes relevant, especially in sedimentary basins, which tend to generate or amplify surface wave components carried by the s...
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Abstract Background In 2020, the number of new cancer cases was estimated at 20 490 862 worldwide up from 18.1 million in 2018 and 14.1 million in 2012. Since the 2000s, cancer treatments have significantly improved, all...
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Drug pharmacodynamics (PD) and pharmacokinetics (PK) are both strongly impacted by drug membrane crossing events. Such an event often involves membrane drug transporters that are divided into two main superfamilies, name...
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While memory effects emerge from systems of wildly varying lengthscales and timescales, the reduction of a complex system with many interacting elements into one simple enough to be understood without also losing the com...
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The endocannabinoid system is recognized as an important player in neuromodulation in the central nervous system (CNS). It comprises cannabinoid receptors, endogenous molecules called endocannabinoids (eCBs) that activat...
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Toxicity mediated by per-and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ...
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T cells use their T cell receptors (TCRs) to discriminate between lower-affinity self and higher-affinity foreign peptide major-histocompatibility-complexes (pMHCs) based on the TCR/pMHC off-rate. It is now appreciated t...
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Congenital clasped thumb is a rare congenital deformity characterized by a permanent contracture of the thumb metacarpo-phalangeal joint. Surgical option often raise in case of failure of the orthopaedic method. We wante...
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Recent studies have developed a systematic approach to morphosyntactic variation among Bantu languages, taking well-known and widely attested construction types as a starting point and sketching their distribution across...
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MOx pellets (UO2-PuO2) with high PuO2 content (above 15 wt.% Pu) are regarded as promising nuclear fuel for Sodium cooled Fast nuclear Reactor. Standard pellet fabrication is based on powder metallurgy processes (grindin...