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Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Acute exposure to copper oxide nanoparticles impairs testicular function and sperm quality in adult male albino rats

Lamiaa Hassan, Ibrahem M. A. Hasan, Zeinab Al-Amgad, Hassan Ahmed • SVU-International Journal of Veterinary Sciences (2024)

Copper oxide nanoparticles (CuO NPs) are metallic nanoparticles fulfilling several functions such as good conductivity, catalyst, used in sensors and energy storage devices, and antibacterial characteristics. However, the cytotoxicity and...

DOAJ Open Access (DOAJ) DOI: 10.21608/SVU.2023.226884.1288

Effects of dietary basil (Ocimum basilicum) supplementation on reproductive hormones, semen parameters, and testicular development in Zandi male lambs

Golnor Kosari, Mohammad Ali Norouzian, Behzad Khorrami, Abouzar Najafi • Veterinary and Animal Science (2024)

This study investigated the potential impact of feeding whole plant basil on sperm quality and the concentration of certain reproductive hormones in male lambs. A total of 18 Zandi male lambs with an initial weight of 28.8 ± 2.03 kg were in...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.vas.2024.100338

Green Synthesized Zinc Oxide Nanoparticles Using <i>Moringa olifera</i> Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats

Gomaa Mostafa-Hedeab, Amany Behairy, Yasmina M. Abd-Elhakim, Amany Abdel-Rahman Mohamed et al. • Antioxidants (2023)

This study assessed the possible protective role of green synthesized zinc oxide nanoparticles using Moringa olifera leaf extract (MO-ZNPs) in acrylamide (ACR)-induced reproductive dysfunctions in male rats. ACR (20 mg/kg b.wt/day) and/or M...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox12020361

Mangifera Indica leaf extracts promote hair growth via activation of Wnt signaling pathway in human dermal papilla cells

Haesoo Jung, Da-Min Jung, Sang-Soo Lee, Eun-Mi Kim et al. • Animal Cells and Systems (2022)

The crosstalk between androgens and Wnt signaling pathways is critical in the hair growth cycle. Therefore, natural products that target these two pathways for the inhibition of hair loss are sought after. In this study, we investigated the...

DOAJ Open Access (DOAJ) DOI: 10.1080/19768354.2022.2085790