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Stage-Dependent Within-Individual Comparison Reveals SIV-Specific Activation/Exhaustion Shift in Rhesus Macaques

Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang et al. • Frontiers in Microbiology (2021)

It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2021.704449

Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity

Veronica Obregon-Perko, Amanda Mannino, Jason T. Ladner, Vida Hodara et al. • Frontiers in Cellular and Infection Microbiology (2024)

While simian immunodeficiency virus (SIV) infection is non-pathogenic in naturally infected African nonhuman primate hosts, experimental or accidental infection in rhesus macaques often leads to AIDS. Baboons, widely distributed throughout ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2024.1408245