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Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Review on: Women with Polycystic Ovary Syndrome

Neelam Gusain, Ashish P. Anjankar, Ranjit S. Ambad, Roshan K. Jha et al. • Journal of Pharmacy and Bioallied Sciences (2025)

One of the biggest health issues facing women in their childbearing years worldwide is polycystic ovarian syndrome, or PCOS. PCOS is a prevalent endocrine condition with well-known negative effects on metabolism, reproduction, and cardiovas...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.jpbs_1995_24

The Protective Effect of Sulforaphane against Oxidative Stress through Activation of NRF2/ARE Pathway in Human Granulosa Cells

Sahar Esfandyari, Ashraf Aleyasin, Zahra Noroozi, Maryam Taheri et al. • Cell Journal (2021)

Objective: Sulforaphane (SFN) is a natural free radical scavenger that can reduce oxidative stress (OS) through mediating nuclear factor (erythroid-derived 2)-like 2 (NF-E2-related factor 2 or NRF2)/antioxidant response element (ARE) signal...

DOAJ Open Access (DOAJ) DOI: 10.22074/cellj.2021.7393

A machine-learning approach for predicting the effect of carnitine supplementation on body weight in patients with polycystic ovary syndrome

Dong-Dong Wang, Ya-Feng Li, Yi-Zhen Mao, Su-Mei He et al. • Frontiers in Nutrition (2022)

The present study aimed to explore the effect of carnitine supplementation on body weight in patients with polycystic ovary syndrome (PCOS) and predict an appropriate dosage schedule using a machine-learning approach. Data were obtained fro...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.851275