Academic Articles & Research Papers

UNDERWEIGHT AND SLIMNESS AND THEIR RELATION TO DIETARY HABITS AND BLOOD PRESSURE AMONG SAUDI FEMALE STUDENTS IN TAIBAH UNIVERSITY

Background: Underweight is a term describing a human whose body weight is considered too low to be healthy. Underweight is associated with negative health consequences, such as nutritional deficiency, osteoporosis, and unfavorable pregnancy...

Bone turnover markers and parameters of functional and structural state in patients with chronic spinal cord injuries in 5 years and later after the trauma

Актуальность. Увеличение продолжительности жизни пациентов с травмой позвоночника и спинного мозга (ТПСМ) привлекло внимание к поздним осложнениям ТПСМ, в частности к остеопорозу. Цель исследования — оценить структурно-функциональное состоя...

Expression of Renal Vitamin D and Phosphatonin-Related Genes in a Sheep Model of Osteoporosis

Osteoporosis is a significant public health issue around the world, with post-menopausal osteoporosis due to estrogen deficiency resulting in approximately ¾ of cases. In this study, 18 aged Merino ewes were ovariectomized, and 10 were cont...

Health Technology Assessment in Osteoporosis

We review the various aspects of health technology assessment in osteoporosis, including epidemiology and burden of disease, and assessment of the cost-effectiveness of recent advances in the treatment of osteoporosis and the prevention of ...

A Focus on Simulation in Medical Informatics

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

Denosumab and Bisphosphonate Treatment of Osteoporosis in Renal Transplant Recipients

Objective: Kidney transplant recipients are at risk of losing bone mineral density. Osteoporosis and fractures cause serious complications in renal transplant recipients. We aimed to evaluate the efficacy and safety of bisphosphonate and de...

Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

Abstract Background Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to va...

The Rising Era of “Immunoporosis”: Role of Immune System in the Pathophysiology of Osteoporosis

Rupesh K Srivastava, Leena Sapra Immunoporosis Lab, Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, IndiaCorrespondence: Rupesh K Srivastava, Tel +91 11-26593548, Email rupesh_srivastava13@ya...

Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study [version 3; peer review: 2 approved, 1 approved with reservations]

Background High quality shared decision-making (SDM) conversations involve people with or at risk of osteoporosis and clinicians working together to decide, where appropriate, which evidence-based medicines best fit the person’s life, belie...

Mobile App Prototype in Older Adults for Postfracture Acute Pain Management: User-Centered Design Approach

BackgroundPostfracture acute pain is often inadequately managed in older adults. Mobile health (mHealth) technologies can offer opportunities for self-management of pain; however, insufficient apps exist for acute pain management after a fr...

From neuromodulation to bone homeostasis: therapeutic targets of nerve growth factor in skeletal diseases

The skeletal system is an important support structure in the human body, and its homeostatic state is highly relevant to the development of a wide range of orthopaedic diseases. The search for key regulatory factors associated with skeletal...

The Patent Landscape of AI-Based Imaging Diagnostics for Osteoporosis: A Scoping Review.

Diagnostic utility of body fat distribution parameters in distinguishing osteosarcopenia from osteoporosis or sarcopenia alone in postmenopausal women: a retrospective cross-sectional study.

Identification of key genes and mechanistic exploration of metabolic reprogramming in osteoporosis.