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Showing 6 of 6 academic articles

LncRNA-Top: Controlled deep learning approaches for lncRNA gene regulatory relationship annotations across different platforms

Weidun Xie, Xingjian Chen, Zetian Zheng, Fuzhou Wang et al. • iScience (2023)

Summary: By soaking microRNAs (miRNAs), long non-coding RNAs (lncRNAs) have the potential to regulate gene expression. Few methods have been created based on this mechanism to anticipate the lncRNA-gene relationship prediction. Hence, we pr...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2023.108197

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience (2021)

Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2021.685143

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis

Chinmay Saha, Sayantan Laha, Raghunath Chatterjee, Nitai P. Bhattacharyya • Non-Coding RNA (2021)

Altered expression of protein coding gene (PCG) and long non-coding RNA (lncRNA) have been identified in SARS-CoV-2 infected cells and tissues from COVID-19 patients. The functional role and mechanism (s) of transcriptional regulation of de...

DOAJ Open Access (DOAJ) DOI: 10.3390/ncrna7040074

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

Linda Nötzold, Lukas Frank, Minakshi Gandhi, Maria Polycarpou-Schwarz et al. • Scientific Reports (2017)

Abstract In recent years, long non-coding RNA (lncRNA) research has identified essential roles of these transcripts in virtually all physiological cellular processes including tumorigenesis, but their functions and molecular mechanisms are ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-02357-0