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Tirzepatide versus GLP-1 receptor agonists and stroke in patients with atrial fibrillation and type 2 diabetes

Chih-Lang Lin, Kuan-Chou Lin, Jung-Min Yu, Chia-Lun Chang et al. • Nature Communications (2026)

Abstract Patients with atrial fibrillation and type 2 diabetes remain at high risk of stroke despite anticoagulation and glucose-lowering treatment. We examined whether tirzepatide was associated with lower cerebrovascular risk than establi...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-026-77047-5

Clustering of Unhealthy Lifestyle and the Risk of Adverse Events in Patients With Atrial Fibrillation

So-Ryoung Lee, Eue-Keun Choi, Eue-Keun Choi, Sang-Hyeon Park et al. • Frontiers in Cardiovascular Medicine (2022)

BackgroundLittle is known regarding the risk of clinical outcomes depending on the clustering of lifestyle behaviors after atrial fibrillation (AF) diagnosis. This study evaluated the association between a cluster of healthy lifestyle behav...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2022.885016

Application of TyG index and carotid ultrasound parameters in the prediction of ischemic stroke

Huimin Guo, Huimin Guo, Sen Wang, Haizheng Wang et al. • Frontiers in Endocrinology (2025)

ObjectiveThe triglyceride - glucose (TyG) index has been confirmed as an independent risk factor for ischemic stroke (IS) in numerous studies. In terms of the role of carotid ultrasound in the risk assessment of IS, the focus has shifted fr...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2025.1481676

Spatiotemporal analysis of hospitalizations, mortality and access to intravenous thrombolysis for ischemic stroke in Southern Brazil

Samile Bonfim, Miyoko Massago, Vinicius Lopes Giacomin, Matheus Henrique Arruda Beltrame et al. • BMC Public Health (2026)

Abstract Background Globally, stroke is a leading cause of mortality and disability, affecting approximately 15 million people annually. This study aimed to analyze hospitalizations, deaths, and thrombolysis for ischemic stroke in Southern ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-026-27097-7

Specificity Protein 1: A Protein With a Two-Sided Role in Ischemic Stroke

Qinyang Yu, Qinyang Yu, Wangyang Liu, Wangyang Liu et al. • Frontiers in Cellular Neuroscience (2021)

Stroke is one of the leading causes of death and disability worldwide. However, there is a lack of effective medications to speed up the recovery process. Ischemic stroke, as the result of cerebral infarction or cerebral artery narrowing, i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fncel.2021.757670

Emerging Role of Ferroptosis in the Pathogenesis of Ischemic Stroke: A New Therapeutic Target?

Zhong-Qi Bu, Hai-Yang Yu, Jue Wang, Xin He et al. • ASN Neuro (2021)

Ischemic stroke is one of the main causes of high morbidity, mortality, and disability worldwide; however, the treatment methods are limited and do not always achieve satisfactory results. The pathogenesis of ischemic stroke is complex, def...

DOAJ Open Access (DOAJ) DOI: 10.1177/17590914211037505

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)