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ROS/Enzyme Dual-Responsive Drug Delivery System for Targeted Colorectal Cancer Therapy: Synergistic Chemotherapy, Anti-Inflammatory, and Gut Microbiota Modulation

Xin Zhang, Ruonan Lian, Bingbing Fan, Lei Meng et al. • Pharmaceutics (2025)

Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, driven by chronic inflammation, gut microbiota dysbiosis, and complex tumor microenvironment interactions. Current therapies are limited by systemic toxicit...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17070940

The Effect of Hydrated Sodium Calcium Aluminosilicate on Fatty Liver and the Composition of the Intestinal Microbiota in Overfed Landes Geese

J Tang, Q Fang, M Lu, R Shao et al. • Brazilian Journal of Poultry Science

ABSTRACT Goose fatty liver is a delicious food product and the overfeeding will cause the abnormal physiology of the geese. The objective of this study was to investigate the effect of supplementation with hydrated sodium calcium aluminosil...

DOAJ Open Access (DOAJ) DOI: 10.1590/1806-9061-2017-0499

The Effects of Deoxynivalenol on the Ultrastructure of the <i>Sacculus Rotundus</i> and <i>Vermiform Appendix</i>, as Well as the Intestinal Microbiota of Weaned Rabbits

Chunyang Wang, Libo Huang, Pengwei Wang, Quancheng Liu et al. • Toxins (2020)

Deoxynivalenol (DON) is a mycotoxin found in grains that poses a potential threat to human and animal health, and the gastrointestinal tract is the primary target organ. There are few studies focused on the toxicology of DON to rabbits, esp...

DOAJ Open Access (DOAJ) DOI: 10.3390/toxins12090569

Exploring the Intestinal Microbiota and Metabolome Profiles Associated With Feed Efficiency in Pacific Abalone (Haliotis discus hannai)

Wenchao Yu, Wenchao Yu, Yisha Lu, Yisha Lu et al. • Frontiers in Microbiology (2022)

Feed efficiency (FE) is critical to the economic and environmental benefits of aquaculture. Both the intestines and intestinal microbiota play a key role in energy acquisition and influence FE. In the current research, intestinal microbiota...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.852460

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

Rebecca I. Clark, Anna Salazar, Ryuichi Yamada, Sorel Fitz-Gibbon et al. • Cell Reports (2015)

Alterations in the composition of the intestinal microbiota have been correlated with aging and measures of frailty in the elderly. However, the relationships between microbial dynamics, age-related changes in intestinal physiology, and org...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2015.08.004

A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin

Eva Klingberg, Maria K. Magnusson, Hans Strid, Anna Deminger et al. • Arthritis Research & Therapy (2019)

Abstract Background Ankylosing spondylitis (AS) shares many characteristics with inflammatory bowel disease (IBD). Intestinal microbiota most likely plays an important role in the development of IBDs and may also be involved in the pathogen...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-019-2018-4