Academic Articles & Research Papers

Association of HCMV IE1 protein and UL123 DNA with clinicopathological features and survival in patients with glioma.

Tumor-targeted pan-RAS inhibition as a novel biologic therapy for diffuse midline glioma.

Exposure-aware multi-omics and artificial intelligence for biomarker discovery and precision prevention in diffuse glioma.

Spatial Omics in High-Grade Gliomas: Mapping Immune-Tumor Niches for Precision Therapy.

State of high-grade glioma care in Africa: insights from a scoping review of the available published literature.

P12.52.A REAL-WORLD DATA COLLECTION FOR LOWER GRADE GLIOMA: EXPERIENCE FROM AROUND THE WORLD.

Deep learning-based segmentation, grading and genotype classification of glioma: a literature analysis.

Cohort-level proportions of low-grade glioma (WHO grades I-II) in mixed glioma cohorts: a single-arm meta-analysis for epidemiological benchmarking and clinical trial design.

Mutations to Medicine: Advances in Medical Management of Paediatric, Adolescent, and Young Adult Low-Grade Gliomas.

From Target Discovery to Spatial Delivery: A Translational Roadmap for Gene-Targeted Therapies in Glioma.

Intranasal nano-immunotherapy for glioma: bypassing the blood-brain barrier, reprogramming the immune microenvironment, and bridging preclinical validation.

Identification and Functional Assessment of the First Placental Adhesin of Treponema pallidum That May Play Critical Role in Congenital Syphilis

Syphilis is a global, re-emerging sexually transmitted infection and congenital syphilis remains a major cause of adverse pregnancy outcomes due to bacterial infection in developing nations with a high rate of fetus loss. The molecular mech...

Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications

Yusi Liu, Xue Song, Moli Wu, Jiao Wu, Jia Liu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, People’s Republic of ChinaCorre...

Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative

Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...

Study of mutations in IDH1 and IDH2 genes in a sample of gliomas from Colombian population

Introduction: Gliomas are the most common primary tumors of the central nervous system and, according to their malignancy, they are graded from I to IV. Recent studies have found that there is an association between gliomas and mutations in...

miRNA-mediated loss of m6A increases nascent translation in glioblastoma.

Within the glioblastoma cellular niche, glioma stem cells (GSCs) can give rise to differentiated glioma cells (DGCs) and, when necessary, DGCs can reciprocally give rise to GSCs to maintain the cellular equilibrium necessary for optimal tum...

Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T

Recent technological progress in the multiband echo planer imaging (MB EPI) technique enables accelerated MR diffusion weighted imaging (DWI) and allows whole brain, multi-b-value diffusion imaging to be acquired within a clinically feasibl...

Alterations in white matter fiber density associated with structural MRI and metabolic PET lesions following multimodal therapy in glioma patients

BackgroundIn glioma patients, multimodality therapy and recurrent tumor can lead to structural brain tissue damage characterized by pathologic findings in MR and PET imaging. However, little is known about the impact of different types of d...

Unrevealing the dual role of paired box and sex determining region Y related high mobility group box in glioblastoma

Abstract This narrative review summarises glioblastoma (GBM), a very frequent invasive kind of brain tumour in the elderly that is extremely aggressive, resistant to treatment, and has a bad prognosis because of its substantial genetic and ...