Academic Articles & Research Papers

Scavenger receptor MARCO contributes to cellular internalization of exosomes by dynamin-dependent endocytosis and macropinocytosis

Abstract Macrophage receptor with collagenous structure (MARCO) is a scavenger receptor class-A protein that is expressed on the cell surface of macrophages. MARCO mediates binding and ingestion of unopsonized environmental particles, inclu...

Relative risk of suicide following exposure to recent stressors, Victoria, Australia

Abstract Objective: This study aimed to identify stressors over‐represented in the 12 months prior to death among 553 Victorian adults who died by suicide. Methods: Age‐ and sex‐specific suicide rates and relative risks of suicide were calc...

Nanotechnology’s frontier in combatting infectious and inflammatory diseases: prevention and treatment

Abstract Inflammation-associated diseases encompass a range of infectious diseases and non-infectious inflammatory diseases, which continuously pose one of the most serious threats to human health, attributed to factors such as the emergenc...

The increase in cases and deaths from malaria in the Brazilian Yanomami territory is associated with the spread of illegal gold mining in the region: A 20-year ecological study

Niezwykle rzadki przypadek nowotworu złośliwego – kosmówczaka u 24-letniego mężczyzny – trudności w diagnostyce różnicowej uszkodzeń śródczaszkowych w aspekcie opiniowania sądowo-lekarskiego

Diagnostyka różnicowa zmian chorobowych i urazowych oparta o wyniki badań obrazowych, w szczególnych przypadkach może nastręczać poważne trudności, a nawet być przyczyną błędu medycznego i w konsekwencji wydania nieprawidłowej opinii sądowo...

MRI Application in Quantification of Epiphyseal Development in the Wrist and Bone Age Estimation of Han Male Adolescents in East China

ObjectiveTo investigate the value of wrist MRI in bone age estimation for male adolescents in Shanghai, Zhejiang and Jiangsu.MethodsA total of 124 Han male adolescents aged 6.0 to 18.0 years from Shanghai, Zhejiang and Jiangsu were selected...

Forensic Discrimination of White Architectural Paints via ATR FT-IR Spectroscopy and Chemometrics

The present work entailed the comparative examination and discrimination of white architectural paint samples of different brands/manufacturers. The analysis of this evidence can facilitate exhibiting a linkage between the victim, and the c...

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

Corrigendum: The Potential Roles of Very Low Calorie, Very Low Calorie Ketogenic Diets and Very Low Carbohydrate Diets on the Gut Microbiota Composition

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Marker

The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, ...

DETECTION & DIFFERENTIATION OF SOFT TISSUE INJURIES IN ADVANCE MAGNETIC RESONANCE IMAGING (MRI)

ABSTRACT BACKGROUND: Radiology is the application of the science of diagnostic imaging to questions of clinical and medicolegal practice. Forensic medicine refers to the application of medical knowledge in the collection of medical evidence...

Performance of Different Cotton and Nylon Swabs on DNA Recovery and Storage

Touch DNA samples are routine yet challenging pieces of evidence that provide investigators with information that helps them solve crimes. However, this type of evidence can be easily lost if the correct collection method is not used. This ...

Human rights and humanitarian forensic action: the experience in Uruguay

Humanitarian Forensic Action (HFA) is considered a new field of Forensic Medicine and Forensic Sciences where the forensic science is applied to different humanitarian activities. In Uruguay, the HFA has been developed based on internationa...

Bacterial Succession in Microbial Biofilm as a Potential Indicator for Postmortem Submersion Interval Estimation

Bacteria acts as the main decomposer during the process of biodegradation by microbial communities in the ecosystem. Numerous studies have revealed the bacterial succession patterns during carcass decomposition in the terrestrial setting. T...

Research Progress on Discrimination of Monozygotic Twins

Individual identification plays an import role in the practice of forensic medicine, and often provides crucial evidence for the analysis and detection of criminal cases. However, for individual identification in complex situations, such as...

Optimization of Bacillus cereus Fermentation Process for Selenium Enrichment as Organic Selenium Source

Selenium is an essential trace element and micronutrient for human health. Application of organic selenium in plants and microorganisms as trace element supplement is attracting more and more attention. In this study, Bacillus cereus, an im...

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

The features analysis of hemoglobin expression on visual information transmission pathway in early stage of Alzheimer’s disease

Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized primarily by cognitive impairment. The motivation of this paper is to explore the impact of the visual information transmission pathway (V–H pathway) on AD, and...

Green Synthesized Zinc Oxide Nanoparticles Using <i>Moringa olifera</i> Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats

This study assessed the possible protective role of green synthesized zinc oxide nanoparticles using Moringa olifera leaf extract (MO-ZNPs) in acrylamide (ACR)-induced reproductive dysfunctions in male rats. ACR (20 mg/kg b.wt/day) and/or M...