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Genomic evolution and stability of the mcr-1-harboring IncI2 plasmid in the presence and absence of colistin

Cong Shen, Meina Wu, Minxuan Su, Hao Wu et al. • BMC Genomics (2025)

Abstract Background The emergence of plasmid-mediated colistin resistance, primarily driven by the mcr-1 gene, represents a major global health threat. IncI2 plasmids, one of the leading carriers of mcr-1, have been frequently recovered fro...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12864-025-12325-y