Academic Articles & Research Papers

Nanocurcumin Attenuates Doxorubicin-Induced Cardiotoxicity by Activating the Wnt/β-Catenin/GSK-3β Signaling Axis in Wistar Rats.

Evaluation of drug delivery performance of curcumin by chitosan synthesized from the skin of the shrimp of the Gulf of Gorgan

Chitosan nanoparticles have emerged as promising carriers for curcumin delivery due to their biocompatibility, biodegradability, and mucoadhesive properties. This study investigates the development and characterization of chitosan nanoparti...

Application of a novel pH-responsive gemini surfactant for delivery of curcumin molecules

During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...

Curcumin Inhibits Growth of Human NCI-H292 Lung Squamous Cell Carcinoma Cells by Increasing FOXA2 Expression

Lung squamous cell carcinoma (LSCC) is a common histological lung cancer subtype, but unlike lung adenocarcinoma, limited therapeutic options are available for treatment. Curcumin, a natural compound, may have anticancer effects in various ...

Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We ...

Key Phytochemicals with Anti-Aging Effects: A Narrative Review

Aging is a multifaceted biological process characterized by a decline in physiological function and increased susceptibility to age-related diseases. This narrative review explored the potential anti-aging effects of phytochemicals-bioactiv...

The Immunomodulatory and Anti-Inflammatory Effect of Curcumin on Immune Cell Populations, Cytokines, and In Vivo Models of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints, causing irreversible cartilage, synovium, and bone degradation. During the course of the disease, many immune and joint cells are activated, causing...

Curcumin: Reintroduced Therapeutic Agent from Traditional Medicine for Alcoholic Liver Disease

Alcoholic liver disease (ALD) is the main cause of chronic liver disease across the world and can lead to fibrosis and cirrhosis. The etiopathogenesis of ALD is related to ethanol-induced oxidative stress, glutathione reduction, abnormal me...

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress

Abstract For this study, we examined the effects of curcumin against acute and chronic stress, paying specific attention to ROS. We also aimed to clarify the differences between acute and chronic stress conditions. We investigated the effec...

Effect of Curcumin on Odontogenic/Osteogenic Differentiation of Dental Pulp Stem Cells

Introduction: Stem cells have gained great attention in tissue engineering and curcumin is a natural phenolic product that had showed some positive effects on these cells. The aim of this study was to evaluate the effect of curcumin on the ...

Evaluating the Antimicrobial Activity of Curcumin-loaded Lipid Nanocarriers When Applying Photodynamic and Sonodynamic Therapy for the Treatment of Skin Infections.