Academic Articles & Research Papers

Anti-plasmodial activity of proteasome inhibitors against various Plasmodium species: a preclinical evaluation.

Accelerated clinical evaluations for Alzheimer's disease: feasibility across specialty and rural care settings.

Synthesis and preclinical evaluation of a novel 2-[(18)F]fluoropyridine-bearing rhodamine for myocardial perfusion imaging with PET.

The relationship between severity of hemorrhoid symptoms and quality of life in Postpartum Women with Grade I and II Internal Hemorrhoid

Introduction: The hemorrhoid is referred to dilated parts of the anal canal veins, which help to control fecal excretion and is one of the most common digestive diseases. Since postpartum problems such as hemorrhoid have significant effect ...

Clinical and epidemiological characteristics in Seychelles patients diagnosed with dementia

Background: dementia has now become a major cause of death, leading to disability and dependence. Objective: to characterize clinical and epidemiological variables in patients with dementia in Seychelles, from July 2018 to August 2019. Me...

Optimization and Clinical Evaluation of a Multi-Target Loop-Mediated Isothermal Amplification Assay for the Detection of SARS-CoV-2 in Nasopharyngeal Samples

SARS-CoV-2 is the coronavirus responsible for COVID-19, which has spread worldwide, affecting more than 200 countries, infecting over 140 million people in one year. The gold standard to identify infected people is RT-qPCR, which is highly ...

Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing

Abstract Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The development of rapid antigen tests has contributed to easing the burden on ...

Developing a Rational, Optimized Product of Centella asiatica for Examination in Clinical Trials: Real World Challenges

Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, i...

Genetic impact of non-consanguineous marriages in Saudi Arabia.

Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients and clinicians. The aim of this study was to estimate the hit rate of the non-consanguineous population. Mor...

Examining the characteristic features of lipedema and the usefulness of BMI and WHtR in clinical evaluation

Abstract Background Lipedema is an adipose tissue disorder involving mostly women. One of the most characteristic lipedema symptoms is painful accumulation of adipose tissue in lower and upper extremities leading to disproportion. Due to th...

Clinical genetics of spondylocostal dysostosis: A mini review

Spondylocostal dysostosis is a genetic defect associated with severe rib and vertebrae malformations. In recent years, extensive clinical and molecular diagnosis advancements enabled us to identify disease-causing variants in different gene...

Computer vision applications in vascular surgery: From preoperative mapping to intraoperative flow assessment

Artificial intelligence (AI) and computer vision (CV) are increasingly applied in vascular surgery for preoperative mapping and intraoperative flow/perfusion assessment, with potential to enhance safety and efficiency. However, the extent o...