Academic Articles & Research Papers

Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review

Abstract Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In TCM theory, patchou...

Bispecific antibodies targeting B-cell maturation antigen in multiple myeloma: Current clinical applications, challenges and future directions.

Biomarkers for the diagnosis and management of cardiovascular-kidney-metabolic syndrome: recent advances and prospects for clinical application.

Bidirectional relationship between diabetes and pancreatic cancer: from mechanistic investigation to clinical application.

Clinical Applications, Opportunities, and Implementation Challenges of AI in Emergency Medicine: A Narrative Review.

Data-Driven Development of Biomedical Hydrogels for Controlled Drug Delivery: Clinical Applications and Emerging Machine-Learning Approaches.

Support Vector Machine Models for Cancer Detection and Related Clinical Applications Using Omics and Omics-Adjacent Data: A Systematic Review.

Alterations in Hip and Knee Joint Contact Force Waveforms and Orientation Induced by Gait Modifications: A Case Study

Introduction & Purpose Idiopathic torsional deformities of lower limb bones can affect a patient’s gait pattern and joint health, while their cause remains unidentified (Koller et al., 2026). Abnormal joint loadings and the progression of ...

Evaluation of Natural Extracts as Promising Components of Bioactive Coatings for Orthopedic Implants

The development of drug-eluting bioactive coatings for orthopedic implants has gained increased interest in recent years with an intent to reduce postoperative complications and improve tissue regeneration at the implant interface. Due to t...

Process-Programmed Extraction–Structure–Activity Relationships (ESAR) in edible and medicinal mushroom polysaccharides: a mechanistic and application-oriented framework

Background: Edible and medicinal mushroom polysaccharides (EMMPs) display wide-ranging bioactivities, yet progress has been limited by siloed workflows. Extraction, structural analysis, and biological evaluation are often conducted independ...

Nanotechnology and its Applications in Medicine

Nanotechnologyis the study of extremely small structures, having size of 0.1 to 100 nm. Nano medicine is a relatively new field of science and technology. Brief explanation of various types of pharmaceutical nano systems is given. Classific...

Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose...

Glass as a biomaterial: strategies for optimising bioactive glasses for clinical applications

Bioactive glasses were the first synthetic materials to bond to human body tissue, making them ideal for replacing and regenerating bone. Since their first development over half a century ago, many new bioactive glass compositions have been...

Application of a novel pH-responsive gemini surfactant for delivery of curcumin molecules

During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...

Cerebrospinal fluid-stem cell interactions may pave the path for cell-based therapy in neurological diseases

Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...

Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults

Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV...

Illuminating the future of diabetes treatment: Autologous CiPSC-derived islets take center stage

The recent clinical success of chemically induced pluripotent stem cell (CiPSC)–derived islet transplantation for type 1 diabetes represents a landmark achievement in regenerative medicine. This article delves into the groundbreaking work p...

Vesicular Carriers for Phytochemical Delivery: A Comprehensive Review of Techniques and Applications

Natural substances, especially those derived from plants, exhibit a diverse range of therapeutic benefits, such as antioxidant, anti-inflammatory, anticancer, and antimicrobial effects. Nevertheless, their use in clinical settings is freque...

Positron emission tomography: establishing priorities for health technology assessment.

BACKGROUND: Positron emission tomography (PET) is an expensive diagnostic imaging technology. Despite the long history of PET development, the costs and effectiveness of its use in routine clinical practice remain unknown. Against this back...